Trying to work out various test results! Any help?

User

Posted 15 Jan 2026 at 14:15

Hi, 64 year old hubby is undergoing assessment and has had PSA of 8.1 with nodules found on DRE. MRI showed PiRad 2 in both peripheral zones plus a pirads 3 lesion in left apical zone. His PSA density was calculated as 2.0 which is higher than the 0.15 cut off I think.
So would this result in a transperineal biopsy? We have to wait a while to see the consultant.

User

Posted 15 Jan 2026 at 16:15

It is always hard to know as we are just amateurs on this site. Nearly everything you've said would point to a biopsy as next axtion, except the lowish Pirads scores. On balance I would say a biopsy is highly likely.

Dave

User

Posted 15 Jan 2026 at 16:22

Hi, Ali.

I'm sorry that your husband may be having prostate problems. However, it's great that you've joined 'our club' to help him. Welcome to the forum.

I agree with everything Dave has said.

PSA tests and MRI scans are just indicators that something maybe amiss. His PSA is elevated, but this may be caused by non-cancerous conditions. Only a biopsy can say whether there is any prostate cancer, and IF SO, how aggressive its likely to be.

Please keep us updated and good luck.👍

Edited by member 15 Jan 2026 at 16:38 | Reason: Additional text

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