PSA Stabilisation after ht/rt

User

Posted 22 Jan 2026 at 09:28

Hi, I am 64 years old, first diagnosed in may 2021, with a psa of 50.6, gleason 4 + 4 , T3b N0 M0.

I had 2years of HT and 37 sessions of RT, which brought my psa to a nadir of 0.03.

Since then, my checks have been 0.16, 0.22, 0.46, 0.49, 0.63, 0.62, 0.78, which is my latest almost two and a half years after the end of my HT.

I would be interested to know if anyone who had HT/RT has had similar readings, or at what level did your psa settle down and stabilise?

My testosterone is currently at 15.

User

Posted 22 Jan 2026 at 22:24

Do you have more Testosterone results, and can you put them with any of the PSA results?

Without knowing what your Testosterone has been doing over this period makes it impossible to know if the PSA is expected. Basically, once your Testosterone settles to a stable value, you would expect your PSA to do so 3-6 months later, but I can't tell from your data if or when your Testosterone became stable.

User

Posted 22 Jan 2026 at 23:29

Hi Andy , all I can really tell you is my last check 15 weeks ago testosterone was 16, so I'm assuming it may be stabilising now, I was supposed to have it checked each time but urology have been dreadful at organising it, and at first wouldn't even let me have one, saying they didn't think it necessary. So psa 15 weeks ago was 0.62 T was 16, this time Psa was 0.78 T was 15.

User

Posted 23 Jan 2026 at 00:36

That's not really enough data. Include a Testosterone test next time, and if PSA is still rising but Testosterone has stayed the same, that might suggest you have some active cancer.

Whether they will do anything before you get to a PSA of 2.03, I don't know. In theory a PSA of 0.2 or 0.5 (depending on the scanner) has a 50% chance of showing up on a PSMA PET scan. However, much of your PSA will be due to healthy cells in the prostate, and to account for them, you want to take away the PSA value at the point 3-6 months after your Testosterone stabilised. You are probably past the point where the remaining level is above these threshholds where something might show on a PSMA PET scan, and even more likely after the nest PSA test.

I would definitely try and have a meeting with your consultant to discuss.

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