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Results.....bitter sweet

User
Posted 18 Mar 2026 at 13:17

Hello, 

Please have a read of my profile which details our journey so far.

So as some of you are aware, Paul has recently been for scans due to psa rise, he has no new symptoms. 

Good news - bone scan show improvement in 2 mets (L1 spine and pelvis), no progression in other 4 mets

Not so good news - CT scan has shown new lesion on L2 spine (strangely not shown up on bone scan‍) and psa has now risen to 4.....increase of 1.5.

No organ or lymph nodes involvement.

Next steps - appointment with Oncologist next week, there is a question of whether Paul has already moved from castrate sensitive to castrate resistant disease which obviously reduces treatment choices and likely have poorer prognosis although I am not sure why the are talking about him becoming resistant already when he has only just taken the Abireratone, he hasnt tried anything else? Usually resistance happens 2-3 years at least into treatment so this is a massive blow. 

Paul has to have biposies taken too, these weren't done on initial diagnosis due to high volume disease and because he started Degarelix straight away but now they must be done to decide on treatments moving forward. 

PSA bloods remain monthly, scans to be repeated in 3 months.

Any words of advice greatly appreciated. I will update my profile too💙

User
Posted 18 Mar 2026 at 14:31
Hi Polly

Can’t offer any ‘advice’ as we’ve not been down the same route/journey as you have…but hopefully those that have will respond and offer some wise words.

This journey sure is a roller coaster and all we can do is take one day at a time, allow ourselves the ‘lows’ then pick ourselves up and fight on!

All the best

Debbie

User
Posted 19 Mar 2026 at 06:19

Hello Polly

I have read the profile.  I am a bit surprised that no PET-PSMA scan has been done to find out the extent of the metastasis.  Also that 177Lu treatment is not one the list as potential treatment options.

 

Good luck with the oncologist.. 

All the best

Crispin

User
Posted 19 Mar 2026 at 08:57

Lutetium 177 is not available on the NHS (except as part of a trial in the past).

 
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