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PSA fluctuating between 5.6 and 7.5 - should I be concerned

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Posted 25 Apr 2026 at 18:28

Hi folks,

Just checking in and looking for a bit of feedback on experience with a fluctuating PSA and at what point any action was taken.

My PSA has jumped from 5.6 to 7.5 over the past 12 months (usually tested every 3 months albeit latest 6 week test dropped back to 7.1).

Urology don't appear concerned and looking to hear back in another 3 months.  This however represents approx 3x the "standard" velocity of 0.75 and surprised I have not been called for an MRI (in Scotland).

Previous MRI's have been clear but subsequent biopsy in Sep 24 triggered a diagnosis and Gleason score of 6.  

I appreciate these numbers are all at the low end of the scale but family history in this area is not good as my brother was diagnosed late and passed away age 52 (he was my older brother at the time and I am now 62).

Also the various activities that can cause PSA to fluctuate don't apply as not currently cycling and also been married over 30 years !!!  I do however keep fit and active in the gym and running but not aware this causes issues.

Any thoughts / past experience on when Urology start to get excited and should I be seeking a second opinion ?

Many thanks

Richard

 

 
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