Notification

Error

How bad is fatigue with Prostap.

User
Posted 29 Jun 2026 at 21:50

Hi, i have just been diagnosed last week stageT2/stageT3a and the plan is to put me on hormone treatment with Prostap next week for six months and start radiotherapy in approximately four months.  Fatigue is one of the side effects and it is often referred to as severe or persisting i am wondering whether to cancel a gentle walking holiday abroad in two months time. Is the fatigue bad for everyone or just some people.

Edited by member 30 Jun 2026 at 11:24  | Reason: Not specified

User
Posted 29 Jun 2026 at 23:53

Yes, there is fatigue, but I found the joint aches the worst side effect. So bad in fact that I went for a bilateral subcapsular orchidectomy!!! No balls, so no more prostap!!!

However, your gentle walking holiday may help both these symptoms. I went for the nuclear option because I have advanced prostate cancer and I was told I would be on prostap for life.

Edited by member 29 Jun 2026 at 23:55  | Reason: Positivity

User
Posted 30 Jun 2026 at 08:11

Hi Ridgerunner

Sorry that you are here with us all, but this is a good place to hang out and get some questions answered ...

If you click on our "avatars" the pictures and/or our names you should be able to see a profile of the person responding.

I am not on Prostap.  I am on HT though.

I am on triplet therapy which is a mix of HT and chemotherapy which will likely be followed by radiotherapy. So I get a double dose of HT (Zoladex and Darolutamide ) and fatigue is an issue.  However the best response to this fatigue is to exercise! I walk as much as I can (10k steps a day) use an indoor bike, weights and resistance bands and have just joined the PureGym programme for those of us on HT (free membership for a year - look it up).

I also have recently taken up yoga.

OK I get tired but then head on out, get the legs moving and after a short while can get into a stride - albeit not at the pace I used to be able to do!

Use walking poles if able, make sure you drink 2 litres a day and I have found that a small foldable seat pad is useful.

Hope this helps your thinking - and do check your travel insurance policy....

 

 

Best wishes - stay positive

CeePee

Show Most Thanked Posts
User
Posted 29 Jun 2026 at 23:53

Yes, there is fatigue, but I found the joint aches the worst side effect. So bad in fact that I went for a bilateral subcapsular orchidectomy!!! No balls, so no more prostap!!!

However, your gentle walking holiday may help both these symptoms. I went for the nuclear option because I have advanced prostate cancer and I was told I would be on prostap for life.

Edited by member 29 Jun 2026 at 23:55  | Reason: Positivity

User
Posted 30 Jun 2026 at 08:11

Hi Ridgerunner

Sorry that you are here with us all, but this is a good place to hang out and get some questions answered ...

If you click on our "avatars" the pictures and/or our names you should be able to see a profile of the person responding.

I am not on Prostap.  I am on HT though.

I am on triplet therapy which is a mix of HT and chemotherapy which will likely be followed by radiotherapy. So I get a double dose of HT (Zoladex and Darolutamide ) and fatigue is an issue.  However the best response to this fatigue is to exercise! I walk as much as I can (10k steps a day) use an indoor bike, weights and resistance bands and have just joined the PureGym programme for those of us on HT (free membership for a year - look it up).

I also have recently taken up yoga.

OK I get tired but then head on out, get the legs moving and after a short while can get into a stride - albeit not at the pace I used to be able to do!

Use walking poles if able, make sure you drink 2 litres a day and I have found that a small foldable seat pad is useful.

Hope this helps your thinking - and do check your travel insurance policy....

 

 

Best wishes - stay positive

CeePee

User
Posted 30 Jun 2026 at 20:39

I had Prostap injections for six months prior to radiotherapy and didn't suffer much fatigue.

I've always felt pretty fit and I carried on with my usual walking regime of 4 or 5 miles at least 5 times a week throughout my treatment. I always get a much better night's sleep when I've been out walking and I find the activity works well for my mental health too.

I did get some hot flushes with Prostap. It also killed libido and gave me some breast/nipple tenderness. The latter seemed to take a year or so to get better but I was back to getting normal erections within 2 or 3 months of receiving my final Prostap injection.

I hope the above helps you with your decision and very best wishes for a successful treatment.

 

 
Forum Jump  
©2026 Prostate Cancer UK