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The end of ADT!

User
Posted 10 Jul 2026 at 10:36

 

Today my last Zoladex injection should be out of my system. I shall not miss it and am looking forward to testosterone recovery. In some ways however it has been a bit of a safety blanket. Whilst on it both Testosterone and PSA have been undetectable. So other than the side effects I've felt pretty relaxed, the cancer has been stopped in it's tracks! I feel like I'm now entering the unknown.

Side effects wise I've been pretty fortunate, I've been able to work throughout my treatment. I still weigh about the same, however I appear to have been converting muscle to fat based on my reflection in the mirror! My cholesterol is on the high side too. I've not really had hot flushes. I can fall asleep impressively quickly these days. Family trips to the cinema include a power nap for me, especially in the comfy recliner chairs they have now. If (when) I wake up at night its hard to get back to sleep. Loss of libido and ED are definitely a thing. 

To combat this I've been on Tadalafil, and have a VED though the NHS, though that took about 6 months to get an appointment after giving them a nudge. I purchased tadalafil online to begin with. I've joined a CrossFit gym after getting a free 12 week program through Battle Caner. I think this and generally trying to keep active has help the most physically and emotionally.  I've also got a fantastic wife and family supporting me, they have been through an emotional roller coaster along with me.

I'm on Tamsulosin to help flow, I think the radiotherapy has caused a slight stricture, but other than that all is good, again I think I've been fortunate.

I've been told my testo should recover fully in about 12 months, I'm hoping to see improvements before then, we shall see! My next follow up appointment and blood tests are in September so I guess unlikely to see anything at that point. I was also told it'll be about 18 months to see if treatment has been successful.

All the best to everyone on their journeys

User
Posted 10 Jul 2026 at 12:07

All the very best to you mate. Can only echo what Adrian has already said. You come across as a top bloke and family man. See you on the other side all being well! 

User
Posted 10 Jul 2026 at 14:44

Hi John

I’m 8.1 months since Zoladex ran out and no testosterone recovery for me yet. Still get hot flushes, less frequent than when on it, but (seems to me) more intense. This hot weather isn’t helping that’s for sure !

Cholesterol is up and HbA1c just into the pre-diabetes range. Never came even close before getting on Zoladex and I’m sure that is a major factor for the increases.

Like you I also feel the no/low testosterone is a blessing in disguise, in that it’s starving any cancer that might be still there.  Wife is going through the menopause now, so neither of us has any interest in getting it on. She tells me she’s not ready for the return of the rampant old goat, just yet. So it’s working out quite well for both of us😊

All the best.

User
Posted 10 Jul 2026 at 11:57

Hi, John.

Thanks for the update, mate.

Your post reminded me of how we and our loved ones all have to adapt to this disease. It changes us all. My wife says that I've now become a right miserable git. 🙂 

Anyway, I'm glad that you're seeing the 'light at the end of the tunnel.'

And thanks, while having to deal with these changes, you've still found the time to help others on this site. You're a top bloke, mate. 👍

 

User
Posted 10 Jul 2026 at 13:10

Thanks guys for your kind words, very much appreciated. 

Adrian, speaking of wives, mine has been great, though she has looked a bit put out on the occasions I've dozed off whilst she's been taking to me. 😂

 

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User
Posted 10 Jul 2026 at 11:57

Hi, John.

Thanks for the update, mate.

Your post reminded me of how we and our loved ones all have to adapt to this disease. It changes us all. My wife says that I've now become a right miserable git. 🙂 

Anyway, I'm glad that you're seeing the 'light at the end of the tunnel.'

And thanks, while having to deal with these changes, you've still found the time to help others on this site. You're a top bloke, mate. 👍

 

User
Posted 10 Jul 2026 at 12:07

All the very best to you mate. Can only echo what Adrian has already said. You come across as a top bloke and family man. See you on the other side all being well! 

User
Posted 10 Jul 2026 at 13:10

Thanks guys for your kind words, very much appreciated. 

Adrian, speaking of wives, mine has been great, though she has looked a bit put out on the occasions I've dozed off whilst she's been taking to me. 😂

 

User
Posted 10 Jul 2026 at 14:44

Hi John

I’m 8.1 months since Zoladex ran out and no testosterone recovery for me yet. Still get hot flushes, less frequent than when on it, but (seems to me) more intense. This hot weather isn’t helping that’s for sure !

Cholesterol is up and HbA1c just into the pre-diabetes range. Never came even close before getting on Zoladex and I’m sure that is a major factor for the increases.

Like you I also feel the no/low testosterone is a blessing in disguise, in that it’s starving any cancer that might be still there.  Wife is going through the menopause now, so neither of us has any interest in getting it on. She tells me she’s not ready for the return of the rampant old goat, just yet. So it’s working out quite well for both of us😊

All the best.

User
Posted 10 Jul 2026 at 19:04

That's a big mile stone John. Hope things continue to look up.

User
Posted 11 Jul 2026 at 16:00

Hi John 

Wishing you all the best. Just enjoy life 

Husband is on day 9/20 of the Radiotherapy. Feeling bit tired he's pacing things and going for a walk later. He's on the Decapeptyl, 2 months of Apalutamide, and Sildenafil x4 per month. Also lately the Tadalafil 5mg each day but he's taken 2 a week and was worried it was making him too big! I don't think so but certainly was doing something anyhow is taking every other day he says.

He's doing OK,  we've got to carry on. Hopefully the consultants know the best course. 

 
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