Psa has dropped

User

Posted 10 Jul 2026 at 15:28

I had a PSA of 21 and had biopsy and was told that I had cancer Gleason score of 4::3 and placed on active surveillance yesterday I had PSA test and my PSA has dropped from 21 down to 0.79 how can this happen

User

Posted 10 Jul 2026 at 18:55

You got any symptoms? Why did you go for a test and are you sure it was 0.79?

Edited by member 10 Jul 2026 at 18:56 | Reason: Not specified

User

Posted 10 Jul 2026 at 19:06

I'm 67 was diagnosed 3months ago after biopsy had to have PSA because I have been placed on active surveillance only had test done yesterday results came back today no symptoms only pissing a hell of a lot

User

Posted 10 Jul 2026 at 22:32

The 0.79 sounds unlikely. I'd have thought they'd do a retest. With a psa of 21 I'd want to know whether it's rising. It could be that it came down as it could have been agitated, but down to 0.79 seems odd. Active Surveillance is about watching your psa carefully. I'd ask about a retest.

User

Posted 18 Jul 2026 at 16:41

I am very confused about the measurement numbers.

Can the PSA number be stated in different way? Mine is 8 but has resulted in an aggressive cubriform cancer. Gleeson 9 T3. Cambridge 5

Is the posters second number of 0.79 just a different way of saying it is nearer his 21...possibly 15 or 16 or something like that?

Really confused. Thanks

User

Posted 18 Jul 2026 at 17:42

Hi there my gleeson score is 3-4 =7 T2a Cambridge is 4 still haven't heard from my specialist nurse in seeing the urologists on the 3 August not sure if I need to get another test

User

Posted 18 Jul 2026 at 22:32

0.79. PSA doesn't look right. Suggest you contact your specialist nurse at your hospital and seek an explanation. There is time to have another PSA test and obtain the result before your appointment on 3rd August. PSA tests in the NHS are normally expressed as nanograms per mililitre (ng/ml) and give an identical result as micrograms per litre, another way of expressing it. So often just PSA and a figure is given.

Other ways of considering PSA are the Free to total PSA Ratio, PSA Density and over time the PSA Velocity (Google if you want the definitions) but you would be told if PSA was being considered in one of these ways.

Barry

User

Posted 20 Jul 2026 at 12:38

I think that figure of 0.79 refers to the density of the cancer in the prostate....not the protein levels. Quite different

but check online

User

Posted 20 Jul 2026 at 13:46

I thought that. PSAD is calculated by dividing the PSA level by the prostate volume. If the PSAD is 0.79 and the PSA is 21, I believe that would make the prostate volume 26.6 cc.

Sounds feasible.

I'm very surprised, unless there are other factors involved, why Gross, with a Gleason 7 (4+3) and PSA of 21 that you on on active surveillance?

Edited by member 20 Jul 2026 at 15:21 | Reason: Additional text

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