Notification

Error

Hormone therapy,length of treatment

User
Posted 01 Aug 2026 at 17:13

Hi, first time on any forum, on any subject. Here goes.

I'm 69 and was diagnosed last year with stage 3, Gleason score 9 and cancer spread to local lymph nodes. I'm on a trial (PEARLS), the main aspect being radiotherapy to a wider area.

I was discharged from urology to oncology around early Oct. I had no further opportunity to ask questions and, probably like, most people receiving such bad news, I was in no state to think clearly at this appointment. I was told to immediately start taking pills to stop the androgen spike and to arrange my first hormone injection with the GP asap. I was not given any options for treatment, or even time to think about it and had no medical path to turn to for advice during the intervening period. I felt that I was railroaded with the haste.

One thing that I was told was that the hormone therapy would be from 6 month to 3 years. Being an optimist (or maybe dreamer) I latched on to the 6 months figure. 

I had my radiotherapy earlier this year and am continuing with the injections. The hormone treatment is a big cause for concern: I'm worried about the side effects, in particular the risk of cardio-vascular disease and osteoporosis, and the total loss of libido. I am getting some side effects but the fhe former is especially worrying as there is a family history.

Because of these concerns I thought to question the oncologist about the length of the hormone treatment (which I’ve been told has to be 3 years). That didn't go down well, espacially as I voiced a desire for a 2nd opinion in the hope that another oncologist might suggest something better.

So what's my point? I was wondering if anyone out there with a similar condition has been offered a different treatment plan, either within the NHS or outside, and how has it gone?

Thanks, in anticipation.

User
Posted 02 Aug 2026 at 05:58

Hello, mate. 

Welcome to the forum. 

I've just done a little Internet research on this trial, and it seems that the period for continued hormone treatment is more likely to be between 18 months and 3 years.  To be on it only 6 months, seems very optimistic.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9550847/

I had surgery, so have no personal experience of prolonged hormone treatment. However, a lot of the lads on here have and I'm sure that some will be along to make comment. I know that many have had unpleasant side effects.

I suppose, you can only be safely advised by those monitoring your trial treatment and it will come down to trying to strike the right balance between the effectiveness of the hormone treatment and the adverse side effects it causes or may cause.

Best of luck.👍

 
Forum Jump  
©2026 Prostate Cancer UK