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Whether to have HDR brachytherapy

User
Posted 25 Aug 2026 at 12:57

Hello,

I am a new member. I hope that you are all as well as possible. 

I am aged 65. I was diagnosed earlier this year with T3b prostate cancer. For various reasons I have decided against high risk RALP surgery. I started taking Relugolix about 6 weeks ago. I now have to make the choice between / I am being offered (1) 6 months Relugolix + High Dose Rate Brachytherapy + 23 sessions of external beam radiotherapy or (2) 24-36 months of Relugolix + 20 sessions of higher dose EBRT. My IPSS is at the lower end of ‘moderate’.

It seems to be a choice between (1) potentially increased chances of 5 and 10 year disease free life and shorter period on hormones (thereby reducing ongoing side effects of hormones) but at the potential cost of increased risk of severe long-term side effects by combing Brachytherapy with EBRT (I am particularly concerned about urinary incontinence or strictures) or (2) having a lower chance of disease free life, but with being on hormones for years (but avoiding the more severe side effects of combing EBRT with HDR brachytherapy).

I would welcome hearing the experiences of others who have had to make a similar decision, and how things have worked out for you.

In addition, I am reluctant to place any reliance on AI and so I would welcome hearing from anyone with reliable data / evidence of (1) the extent of any increased life expectancy by having HDR brachytherapy and EBRT (2) the extent of increased risks of severe side effects of having HDR brachytherapy and EBRT, and (3) whether 6 months on Relugolix plus HDR brachytherapy is as effective as long term hormone treatment plus EBRT.

Thank you for taking the time to read this. With best wishes, 

Bill

User
Posted 25 Aug 2026 at 14:47

Hi Bill,

Welcome to the site and sorry you find you're self here. I was diagnosed March(ish) 2024. Initially recommended  surgery, then a second surgeon said HT/RT was the way to go. He could do the surgery, but it would be none nerve sparing and I'd most likely need salvage RT. The none nerve sparing really put me off, and why have a double wammy of side effects too!

I was due to have 20 sessions of EBRT + 24 months of HT. A few days before I was due to start I was called in and offered 15 sessions plus HDR Brachy, the HT was staying the same. I was warned ED and strictures were more likely, which develop over time especially with EBRT and Brachy combined. I went ahead as anything to reduce the chance of reoccurance. ED still bothered me but I thought I could handle it more if it progressed slowly (fingers crossed not at all!)

I've just finished HT and waiting for testosterone to return

The Brachy was very straightforward too, mine was done under general anesthetic. I walked into the hospital at 7am, and walked out again at 12:45 after proving I could wee ok. This is personal experience so I guess its not always so straight forward

I'm only a short way through the journey, but I'd still add HDR Brachy in, especially if it reduced the time on HT. I never had any hint of incontinence and the ED I'm experiencing is down to the HT from what I can tell. A pump and tadalafil from the NHS is helping mini me through the dark times.

Of all the treatments side effect I've found HT the worst, though hopefully these will wear off over the coming months. I'm on tamsulosin for a possible slight stricture (this is what I assume is the problem, I will query at my next telephone appointment if that's the case). It's only very mild and hasn't got any worse, I've tried stopping the tamsulosin, I was still able to pee but with reduced flow and it felt a bit uncomfortable.

 

All the best

John

 

 

 

 

User
Posted 25 Aug 2026 at 16:39

Dear John

Many thanks indeed for your speedy reply and for sharing your story. It was extremely useful and interesting to hear the detail of your experiences. I understand that we all have different experiences, but still very helpful to hear yours.

Many congratulations on finishing your HT. That’s excellent. I hope that you soon feel free from the impact of the hormones and that you continue to be well.

With all best wishes, and thanks again.

Bill

 

 
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