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After 6 Docetaxel sessions when can I expect to feel more normal?

User
Posted 25 Sep 2026 at 19:49

hi everyone, I finished my sixth Docetaxel session about a month ago. I’m still dealing with various side effects. My question is do people start feeling normal eventually and how long might it take for that to happen?

User
Posted 26 Sep 2026 at 13:03

Hi Engineerken


Firstly congratulations on making it to number 6!  I got to no 6 at the end of May this year.


Remember that the cycle is three weekly, with the third week supposedly with you feeling better to go into the next round. So if your sixth dose was only four weeks ago then you are just about in the starting to feel a bit better phase I would guess.


I found that there was a cumulative effect from the doses, with the recovery period being shorter each time as the bad effect period seemed to get longer... However I kept up my exercise regime of physical activity of weights, resistance bands and static bike and began to feel better after a few weeks, that is until the steroid withdrawal kicked in.  I was given a programme of around six weeks to taper down the steroids until having one dose a week.  I found this really difficult to deal with and the fatigue was extreme - but I pushed through it.


My hair and beard started to come back after about three months, and I lost that podgy steroid face around the same time.  However as I am still on HT I then started to lose body hair around the same time....


I got fit enough to ride in the static bike challenge in Sir Chris Hoy's Tour de 4 three weeks ago and smashed my target of 12km - achieving 15km - in a thirty minute slot.


Just think in months rather than weeks (from my own experience).


Good luck with the recovery - and don't forget to click on our names of roundels to get to our personal stories. 

Edited by member 26 Sep 2026 at 14:49  | Reason: additional text

Best wishes - stay positive


CeePee

User
Posted 27 Sep 2026 at 08:43
Took me about 3 months. One thing that did change even years later I really feel the cold whereas pre chemo I'd go through winter without a coat and rarely put the heating on.
Now in September I'm asking my wife if we can put the heating on.
Seems like the chemo sucked all the natural warmth out of my body.
Conversely when in Spain on holiday in the summer I can sit out in the heat all day, doesn't bother me at all unless she turns the Aircon on in the apartment then I'm cold very quickly.
User
Posted 27 Sep 2026 at 09:01

Hi JasperM


That is an interesting thought about feeling the cold more…


I developed peripheral neuropathy so reduced dosage to 80% from no4 onwards.  I now find that my hands get really cold really quickly and my feet are the same ( funnily enough I was just looking at an email I had from Heat Holders!!)


Stay warm

Best wishes - stay positive


CeePee

User
Posted 27 Sep 2026 at 10:26

Hi


I had 10 rounds of docetaxel a couple of years ago and coped with it well,Unfortunately for me only a few months after finishing the course my psa started to rise again,please read my history for more info.


Good luck with your journey 

User
Posted 28 Sep 2026 at 11:33

Hi Ken


Just start to do a little each day, then a little more - it will get back to you! But with the HT it is a constant - you need to keep up the activity to overcome the fatigue.  Set a goal or two, don't aim too high, make it realistic.  The event I did in Glasgow meant that I didn't have specific targets, the event I went in for on the static bike was actually a timed event, thirty minutes against the peloton (which was a virtual one from around the world) at whatever pace you could manage.  I set myself a 12km goal as that represented 12,000metres - one for every man who dies from PC in the UK each year. As it was I smashed that and rode for 15.2 km in thirty minutes - although I did have an Olympic Gold medallist riding next to me for some encouragement!


My current goal is recovery from an inguinal hernia repair a week ago - it was an open wound of around 12cm (five inches) and two hours in theatre so is taking a bit of time (on top of feeling the usual rubbish from two loads of HT).   My goal is to get fit again so that I can have radiotherapy in mid-November.


Take your time - it will get better!!!


 

Best wishes - stay positive


CeePee

User
Posted 01 Oct 2026 at 11:55

Hi all


Had a discussion with my oncologist this week. After being on Enzalutamide for almost four years it looks like 2027 will be the year of Docetaxel. Not looking forward to it but I’ll post regular updates regarding progress etc. Good luck everyone on your journey xx

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User
Posted 26 Sep 2026 at 13:03

Hi Engineerken


Firstly congratulations on making it to number 6!  I got to no 6 at the end of May this year.


Remember that the cycle is three weekly, with the third week supposedly with you feeling better to go into the next round. So if your sixth dose was only four weeks ago then you are just about in the starting to feel a bit better phase I would guess.


I found that there was a cumulative effect from the doses, with the recovery period being shorter each time as the bad effect period seemed to get longer... However I kept up my exercise regime of physical activity of weights, resistance bands and static bike and began to feel better after a few weeks, that is until the steroid withdrawal kicked in.  I was given a programme of around six weeks to taper down the steroids until having one dose a week.  I found this really difficult to deal with and the fatigue was extreme - but I pushed through it.


My hair and beard started to come back after about three months, and I lost that podgy steroid face around the same time.  However as I am still on HT I then started to lose body hair around the same time....


I got fit enough to ride in the static bike challenge in Sir Chris Hoy's Tour de 4 three weeks ago and smashed my target of 12km - achieving 15km - in a thirty minute slot.


Just think in months rather than weeks (from my own experience).


Good luck with the recovery - and don't forget to click on our names of roundels to get to our personal stories. 

Edited by member 26 Sep 2026 at 14:49  | Reason: additional text

Best wishes - stay positive


CeePee

User
Posted 27 Sep 2026 at 08:43
Took me about 3 months. One thing that did change even years later I really feel the cold whereas pre chemo I'd go through winter without a coat and rarely put the heating on.
Now in September I'm asking my wife if we can put the heating on.
Seems like the chemo sucked all the natural warmth out of my body.
Conversely when in Spain on holiday in the summer I can sit out in the heat all day, doesn't bother me at all unless she turns the Aircon on in the apartment then I'm cold very quickly.
User
Posted 27 Sep 2026 at 09:01

Hi JasperM


That is an interesting thought about feeling the cold more…


I developed peripheral neuropathy so reduced dosage to 80% from no4 onwards.  I now find that my hands get really cold really quickly and my feet are the same ( funnily enough I was just looking at an email I had from Heat Holders!!)


Stay warm

Best wishes - stay positive


CeePee

User
Posted 27 Sep 2026 at 10:26

Hi


I had 10 rounds of docetaxel a couple of years ago and coped with it well,Unfortunately for me only a few months after finishing the course my psa started to rise again,please read my history for more info.


Good luck with your journey 

User
Posted 27 Sep 2026 at 19:43

Sounds like you've had a rough ride, Phil. Best wishes to you. Thanks for your post.

User
Posted 27 Sep 2026 at 19:50

Interesting observation about increased sensitivity to cold. Right now I think I agree but I'll wait a few more months to accept this as permanent. Thanks for the post and the three month prediction of feeling better. I'm looking forward to that.


Ken

User
Posted 27 Sep 2026 at 19:58

Thanks CeePee,


I agree that the side effects are cumulative, especially after sessions #5 and #6. My hemoglobin has dropped quite low and consequently my energy is low and I'm out of breath quickly. I had been walking several miles per week early in the chemo sequence but I couldn't continue after 5 and 6. 


Ken

User
Posted 28 Sep 2026 at 11:33

Hi Ken


Just start to do a little each day, then a little more - it will get back to you! But with the HT it is a constant - you need to keep up the activity to overcome the fatigue.  Set a goal or two, don't aim too high, make it realistic.  The event I did in Glasgow meant that I didn't have specific targets, the event I went in for on the static bike was actually a timed event, thirty minutes against the peloton (which was a virtual one from around the world) at whatever pace you could manage.  I set myself a 12km goal as that represented 12,000metres - one for every man who dies from PC in the UK each year. As it was I smashed that and rode for 15.2 km in thirty minutes - although I did have an Olympic Gold medallist riding next to me for some encouragement!


My current goal is recovery from an inguinal hernia repair a week ago - it was an open wound of around 12cm (five inches) and two hours in theatre so is taking a bit of time (on top of feeling the usual rubbish from two loads of HT).   My goal is to get fit again so that I can have radiotherapy in mid-November.


Take your time - it will get better!!!


 

Best wishes - stay positive


CeePee

User
Posted 01 Oct 2026 at 11:55

Hi all


Had a discussion with my oncologist this week. After being on Enzalutamide for almost four years it looks like 2027 will be the year of Docetaxel. Not looking forward to it but I’ll post regular updates regarding progress etc. Good luck everyone on your journey xx

User
Posted 01 Oct 2026 at 12:39

Hi NellyA


The thought of chemo was a little daunting I must say, but it just seems now to be something in the past that happened and I am on to other things.  Yes I felt really rough, and used the word brutal a couple of times but it actually seemed to go well and the six sessions all went smoothly..


It does take the body a while to recover but it really really helps to be as fit as you can going into it.  Good luck with it all.


 

Best wishes - stay positive


CeePee

User
Posted 02 Oct 2026 at 01:12

Hi NellyA, The first four Docetaxel infusions were quite tolerable. The last two have caused more side effects that have lasted longer. I just passed four weeks since my last infusion and I’m now seeing some relief. Best of luck on your journey. 


ken

 
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