Notification

Error

PSA anxiety ongoing

User
Posted 09 Oct 2026 at 14:50

Hi all,

I'm now 30 months post prostatectomy.

My post op pathology was not what I hoped for, pT3a r1, so I had EPE and a focal positive margin.

Thankfully up to my last test at 27 months my PSA has been undetectable at <0.01.

My next PSA test is next week and as always I'm back to the worrying of whether this will be the one where it becomes detectable again.

What coping strategies do you use to cope with this stress? 

I am on 3 monthly tests as deemed high risk of recurrence. Has anyone been in that position and been moved to 6 month tests and did that help with PSA anxiety.

Cheers,

Mel

User
Posted 09 Oct 2026 at 16:31
It definitely does! Best thing is to plan in your head what you would do treatment wise if you do ever lose the <. That way you know what the worst case scenario is and given you have had a < since your op you have every chase of successful further treatment.
User
Posted 09 Oct 2026 at 16:31
It definitely does! Best thing is to plan in your head what you would do treatment wise if you do ever lose the <. That way you know what the worst case scenario is and given you have had a < since your op you have every chase of successful further treatment.
User
Posted 10 Oct 2026 at 12:31

Hi again Adrian,

Thanks for the really great reply.

Hopefully if I get to 36 months undetectable I can be moved to 6 monthly tests. I think I would cope better with that.

I recall the surgeon at the initial 6 week follow up telling me I would be on 3 monthly indefinitely. I will plead my case if I get to the 36 months.

All the best for your 45 month and subsequent tests.

Mel

Show Most Thanked Posts
User
Posted 09 Oct 2026 at 15:38

Originally Posted by: Online Community Member
What coping strategies do you use to cope with this stress?

Drink, even more than usual. 🍻

User
Posted 09 Oct 2026 at 15:41

Thanks Adrian 🤣. Not sure that would help!

User
Posted 09 Oct 2026 at 16:31
It definitely does! Best thing is to plan in your head what you would do treatment wise if you do ever lose the <. That way you know what the worst case scenario is and given you have had a < since your op you have every chase of successful further treatment.
User
Posted 09 Oct 2026 at 16:31
It definitely does! Best thing is to plan in your head what you would do treatment wise if you do ever lose the <. That way you know what the worst case scenario is and given you have had a < since your op you have every chase of successful further treatment.
User
Posted 10 Oct 2026 at 09:54

Originally Posted by: Online Community Member
I am on 3 monthly tests as deemed high risk of recurrence. Has anyone been in that position and been moved to 6 month tests and did that help with PSA anxiety.

Hi, Mel.

I'm pretty sure we've chatted on here before mate. Our diagnoses were pretty similar. I was T3a, EPE, I had negative margins and a lower PSA 7 than yours, but my Gleason was higher at 9 (4+5). 

I had RARP over three and a half years ago. Like you, so far, I've been lucky and had no recurrence, my PSA has remained undetectable at <0.02. However, according to nomograms I still have about a 50% chance of 'it coming back' within the next six years.

https://www.mskcc.org/nomograms/prostate/post_op

As I was at high risk of recurrence, for the first three years after surgery, I was on three monthly PSA tests, which were then changed to every six months.

I'm due my next test, which will be 45 months post op, next month. Although my PSA anxiety has reduced, I still find testing times a testing time. 🙂 I've found that prolonging the time between tests has definitely helped.

I think I read some research, where they'd found, that if your PSA was had remained undetectable for three years after surgery, it was safe to have only annual checks. I'll see if I can find a link to it. As far as I can remember, however, it didnt include men like us who were at higher risk. Anyway, it all sounded a little too risky me for me.

For my own peace of mind, I'm still happy enough to have six monthly checks. It would just be my luck to go to yearly checks, and find the enemy had returned.

I think you'd need to be man of steel to have zero PSA test concerns.

Good luck, mate, and long may those undetectable arrows fly. <<<<<<<<<<<. 👍

Late edit: I couldn't find a link to the the actual research about prolonging the time between PSA tests after surgery but an AI reply suggests it exists 

The 3-Year Risk Threshold: A large-scale European study analyzing risk-based monitoring found that the risk of rapid, aggressive biochemical recurrence (BCR) decreases dramatically after the first three years post-surgery. If a patient's PSA remains completely undetectable during this initial window, moving immediately to annual screening is sufficient and safe. Late recurrences (occurring after several years) typically feature favorable pathology and an exceptionally slow doubling time, meaning they do not require ultra-frequent monitoring

Edited by member 10 Oct 2026 at 10:35  | Reason: Additional text

User
Posted 10 Oct 2026 at 12:31

Hi again Adrian,

Thanks for the really great reply.

Hopefully if I get to 36 months undetectable I can be moved to 6 monthly tests. I think I would cope better with that.

I recall the surgeon at the initial 6 week follow up telling me I would be on 3 monthly indefinitely. I will plead my case if I get to the 36 months.

All the best for your 45 month and subsequent tests.

Mel

User
Posted 10 Oct 2026 at 15:31

Mel

"What coping strategies do you use to cope with this stress?'

My post of PSA was 0.03, positive margins and extra prostatic extension. I hit 0.2 three years post op. Within 6 months of surgery I knew there was likely to be a recurrence. I soon began to understand that worrying about a rise didn't stop the PSA rising. I am twelve years post op and no longer get concerned about rising PSA results,in fact I am not longer concerned about having cancer,I just ask what's next. After salvage RT and having two lymph nodes zapped on two separate occasions, I am now on HT. So even if you do get a recurrence there are plenty of options. 

Thanks Chris.

 

Edited by member 10 Oct 2026 at 15:32  | Reason: Not specified

 
Forum Jump  
©2026 Prostate Cancer UK