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Localised reaction to Prostap injection

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User
Posted 11 Oct 2026 at 09:30

Hi, i had my first Prostap three monthly injection into my upper arm with no obvious local reaction. However my second injection was subcutaneous into the abdomen and within a day caused a hot and red swelling. Is this likely to happen with future injections into the abdomen and would i be better reverting to the upper arm .

David.

User
Posted 11 Oct 2026 at 15:59

It could mean you are allergic to Prostap. Discuss this with your oncologist as they might want to check your Testosterone level before the next injection, and possibly switch you to Zoladex or Relugolix.

I doubt it's anything to do with the injection site, although there is a possibility some infection was introduced during the procedure.

User
Posted 11 Oct 2026 at 16:07

Originally Posted by: Online Community Member

I've always had my Zoladex in alternate sides of the abdomen, I didn't know arm was an option for these type of implants. Last one I had did give me some jip, I mentioned it to the oncologist and he more or less said it was the nurses poor technique. Hopefully this is a one off for you. But I believe it is a known possible side effect.

Zoladex and Staladex are solid implants and have to be in subcutaneous fat in order to slowly dissolve at the intended rate, and I guess were tested in the abdomen, so that's where they have to go.

Prostap and Decapeptyl are depot injections (a fluid which sets on injection into gel which then slowly dissolves), which as far as I know can be injected into fat or muscle.

Relugolix is a daily tablet.

Edited by member 11 Oct 2026 at 16:10  | Reason: Not specified

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User
Posted 11 Oct 2026 at 13:33

I've always had my Zoladex in alternate sides of the abdomen, I didn't know arm was an option for these type of implants. Last one I had did give me some jip, I mentioned it to the oncologist and he more or less said it was the nurses poor technique. Hopefully this is a one off for you. But I believe it is a known possible side effect.

ATB,

hawkz

User
Posted 11 Oct 2026 at 15:59

It could mean you are allergic to Prostap. Discuss this with your oncologist as they might want to check your Testosterone level before the next injection, and possibly switch you to Zoladex or Relugolix.

I doubt it's anything to do with the injection site, although there is a possibility some infection was introduced during the procedure.

User
Posted 11 Oct 2026 at 16:07

Originally Posted by: Online Community Member

I've always had my Zoladex in alternate sides of the abdomen, I didn't know arm was an option for these type of implants. Last one I had did give me some jip, I mentioned it to the oncologist and he more or less said it was the nurses poor technique. Hopefully this is a one off for you. But I believe it is a known possible side effect.

Zoladex and Staladex are solid implants and have to be in subcutaneous fat in order to slowly dissolve at the intended rate, and I guess were tested in the abdomen, so that's where they have to go.

Prostap and Decapeptyl are depot injections (a fluid which sets on injection into gel which then slowly dissolves), which as far as I know can be injected into fat or muscle.

Relugolix is a daily tablet.

Edited by member 11 Oct 2026 at 16:10  | Reason: Not specified

 
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