PSA 0.65 after Radical Prostatectomy

User

Posted 14 Nov 2026 at 12:10

Hi all,

So hubbys journey began in 2018 with Bowel Cancer, tumour was removed and all was well. This year he was diagnosed with PSA 10, Gleason 7 (4+3) T3a. He had radical prostatectomy at UCL in august. Lymph glands and seminal vessels removed and pathology confirmed the Gleason as before, but margins and lymph glands were clear.

3 months on his PSA is 0.65 which apparently indicates 'detectable disease still present' so he's booked in for an urgent PSMA PET scan.

Consultants have told him he can NEVER have radiotherapy, as it would damage his bowel, so if there was a recurrence it would be chemo. But reading up, it appears Chemo never cures it, just keeps it at bay?

Anyone have any experience or knowledge please?

User

Posted 14 Nov 2026 at 16:19

Hi , I also had a very high post surgery psa. Worse than yours to be honest. That was in 2015. I didn’t have salvage RT as it was decided it was in my blood. It eventually was found in spine and ribs and hip 4 yrs later. I’ve been on HT for 6 yrs. In honesty my QOL is okay and I’m profoundly grateful for that. Not had Chemo yet. So don’t give up ok. All cases are different obviously but you may have some years left yet 💪

User

Posted 14 Nov 2026 at 20:05

Dejavu, my PSA crept up slowly after surgery,I did have Salvage RT and that did damage my bladder.I also had SABR treatment to two pelvic lymph nodes. I wouldn't rule out SABR treatment until you know where the hot spots are. I eventually went on to apalutamide tablets and decapeptyl injections. I only take half the normal apalutamide dose and the side effects are bearable.

Thanks Chris

User

Posted 14 Nov 2026 at 23:30

Hi, Chris, nice to hear of you again, such a resilient and supportive guy! ❤️

Good news that you're coping with the side effects of apalutamide. Really glad about that👍🏽

You mentioned that you had SABR to two lymph nodes after having had previous salvage RT -with damage to your bladder-. I assume the area where the spots SABR was given to was a different one to avoid second radiation, or if not, it was cautiously examined to determine whether applying SABR was not harmful?

Best wish, Chris, Dejavu.

Lola.

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