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PSA levels for men

User
Posted 19 May 2014 at 21:18

Reading this reminded me to bring the figures below to the new forum.

http://www.pcf.org/site/c.leJRIROrEpH/b.6185669/k.9792/Sherry_Galloway.htm

 

PSA levels

Men in their 40s = 0.7
Men in their fifties = 0.9
Men in their 60s = 1.3
Men in their 70s = 1.7

http://www.ncbi.nlm.nih.gov/pubmed/21862205

http://www.sciencedirect.com/science/article/pii/S0090429505011970

from

http://community.prostatecanceruk.org/posts/t6693-PSA-Levels-in-Younger-Men#post6693

User
Posted 20 May 2014 at 09:21

trust the BBC to show this link = well done

Prostate cancer may be a sexually transmitted disease caused by a common yet often silent infection passed on during intercourse, scientists say - but experts say proof is still lacking.

Although several cancers are caused by infections, Cancer Research UK says it is too early to add prostate cancer to this list.

 

http://www.bbc.co.uk/news/health-27466853

User
Posted 20 May 2014 at 19:08

I am unclear where the levels for PSA for men through the age range came from.

 

The figures my GP referred to after my initial test came from the NHS guidance which is contained in the following link:

http://www.nhs.uk/Livewell/Prostatehealth/Pages/psa-test.aspx

As extract:

The PSA test is a blood test which can detect the early signs of prostate cancer.

The test, which can be done at a GP surgery, measures the level of PSA (prostate-specific antigen) in your blood.

PSA is made by the prostate gland. Some of it will leak into your blood, and the amount depends on your age and the health of your prostate.

Raised PSA levels

The amount of PSA in your blood is measured in nanograms of PSA per millilitre of blood (ng/ml). PSA levels can range from 1ng/ml to hundreds of ng/ml.

  • If you're aged 50–59, your PSA level is considered raised if it's 3ng/ml or higher.
  • If you're aged 60–69, your PSA level is considered raised if it's 4ng/ml or higher.
  • If you're aged 70 or over, your PSA level is considered raised if it's 5ng/ml or higher.

A raised PSA level in your blood may show that you have a problem with your prostate. However, this may not be prostate cancer.

 

My oncologist post HT & RT treatment stated that if after 18 months my PSA level is below 2ng/ml she will be content that the treatment is successful.

I am now confused by the Original Post. What is the definitive information on PSA levels which indicate a that there is a risk of PCa that require further diagnostic tests? Especially in men in their 40s for which there is no advice that I can find from the NHS.

I ask this as my sons are approaching and age when this will be important to them

Davy

User
Posted 20 May 2014 at 20:12

 

"   EVIDENCE SYNTHESIS:

In most published series, median PSA levels in the general male population range from approximately 0.4 to 0.7 ng/ml in men in their 40s and from approximately 0.7 to 1.0 ng/ml in men in their 50s. Evidence from both nonscreening and screening populations has demonstrated the predictive value of a single baseline PSA measurement for prostate cancer risk assessment. Specifically, men with baseline PSA levels above the age-group-specific median have a greater risk of prostate cancer diagnosis during the next 20-25 yr. Additional studies confirmed that higher baseline PSA levels at a young age are also associated with a greater risk of aggressive disease, metastasis, and disease-specific mortality many years later.

CONCLUSIONS:

Baseline PSA measurements at a young age are significant predictors of later prostate cancer diagnosis and disease-specific outcomes. Thus baseline PSA testing may be used for risk stratification and to guide screening protocols "


from

http://www.ncbi.nlm.nih.gov/pubmed/21862205

also read

http://www.sciencedirect.com/science/article/pii/S0090429505011970

 

 If psa figures fall into the above ranges, then those at higher risk just need to test on a regular basis. If above these median figures then more attention to testing might be required. i.e. more often.

That's the conclusion I reached.

User
Posted 21 May 2014 at 09:15
The figures in Dave’s post are those given to via medical trial (drug company looking for guys with a PSA level in that range to see if a daily pill would prevent PCa) , As mine was above those quoted the PCa journey commenced.

My conclusion would be as Rob’s. How many GP’s will come to the same conclusion and agree to early PSA tests is?

Ray

User
Posted 17 Jun 2014 at 15:59
Dr Chireka: Prostate cancer on the rise, so what?

Dr C paper has a lot of info well put together - wish I had read it all say 4 years ago - watchful waiting is a gamble - but so is life all the time...

Men who have first degree male relatives (such as a father or brother) affected by prostate cancer are at slightly increased risk as well. It is thought that lycopene-rich foods are best in protecting one from the disease. Lycopene is an antioxidant that is commonly found in fruits and vegetables that are red in colour like tomatoes, watermelon and guavas. Chillis of all sorts are also lycopene powerhouses.

http://www.newzimbabwe.com/columns-16233-Dr+Chireka+Prostate+cancer,+what+to+do/columns.aspx

User
Posted 10 Nov 2014 at 20:26

thanks to all above for the info i,m haveing my 1st psa test in a week following months of problems the docs passed off as infections and now nothings worked they finally do the tests and think somethings wrong , question tho has anyone else had to give a urine sample weekly before testing ??

User
Posted 11 Nov 2014 at 20:58

It could be part of the new'ish urine test being monitored for P.Ca. detection or just looking for infection.

Either way, so long as you are now getting full tests & attention.

Best wishes for results & let us know if you glean any more information. Always useful to hear of developments coming into practice.

User
Posted 11 Nov 2014 at 21:23

sure its the same nurse doing both and will ask her why when i see her 

User
Posted 21 Feb 2015 at 20:22

I am on testosterone therapy and had a blood test at the beginning of the month just before my next jab was due and one of the results was a PSA of 12.8. My GP has immediately referred me to a urologist.

I had a blood test at the beginning of this week after my next injection and now my PSA is 1.3

Is a swing like this normal or was one of the tests wrong?

My worry is that they will take me of the testosterone therapy as its a life changer.

User
Posted 21 Feb 2015 at 22:29

Hi Martin, if you did turn out to have prostate cancer, then there may come a time when you would have to stop the testosterone injections as one of the treatments for advanced PCa is hormone treatment to block or stop the production of T. However, if you were diagnosed with early stage cancer and able to have surgery then it might not be an issue.

With a psa that swings from 12 down to less than 2, you may find after all that your prostate is just fine and it is the T injections that are variable!

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

 
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