It has been a while since I last looked on this forum, mainly because of extreme fatigue which made it impossible to sit in front of a computer screen for more than a few minutes at a time.
I was deeply saddened to find out that two of the stalwarts of the forum, David (Colu-fc) and Trevor (Trevor_Boothe) have passed away during my absence.My heart goes out to their families. I am so grateful to Linda and Julie for continuing their stories right to the end. They did that with warmth, compassion and dignity and I, being a person who is not too far behind these two gentlemen, found it very reassuring to know that they passed away so peacefully. I know it is a long time after the event now, but I hope their families have begun to come to terms with their loss. I send Linda and Julie my very best wishes.
My own current status is that having completed six cycles of palliative Docetaxel in February, I am not on any treatment at the moment apart from three monthly injections of Decapeptyl. A CT scan at the end of April showed that all existing tumours are stable and there are no new ones, so something is keeping them at bay. My PSA however has risen from 23 in February to 53 at the beginning of May.
My onco is concerned about the rise in PSA and has said it is now time to consider further treatments. He has offered me three possible options. These are:
1) Further chemotherapy using Cabazitaxel
2) Participation in the TRITON trial alongside Cabazitaxel
3) Participation in the RE-AKT study which includes treatment with Enzolutemide
Participation in either of the trials is of course subject to eligibility and acceptance. I am currently awaiting details of these trials, but I have obviously done my own research on the internet. At the moment, my favoured option is RE-AKT, mainly because it does not involve chemotherapy.
I would be grateful for any thoughts on any of the three options.
In the meantime, I have been feeling quite well since finishing the chemotherapy, but I do still feel the fatigue and I get a lot of quite bad backache and pain around my hips. I am also suffering from diarrhea, alternating with constipation. So my area "around the middle" feels constantly uncomfortable.