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Recurrance

User
Posted 18 Apr 2024 at 03:31

Hi can any of you share any research or studies regarding recurrence after RARP and radiotherapy.  Thanks 

User
Posted 18 Apr 2024 at 03:31

Hi can any of you share any research or studies regarding recurrence after RARP and radiotherapy.  Thanks 

User
Posted 18 Apr 2024 at 19:06

Here's an interesting one

https://community.prostatecanceruk.org/postmessage?t=30507&f=33

See in particular Figure 1 which shows the risk of recurrence, which is fairly high, but then also Figure 2 which shows how, for prostatectomy in particular, the risk of dying after recurrence is actually very low (4%-9%) at least up to 10 years after recurrence, which is actually quite a long time by cancer standards and also given the age of many men who experience recurrence.

User
Posted 18 Apr 2024 at 19:44

My apologies - the link in my previous post should be this one.

 

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2809152

 

User
Posted 19 Apr 2024 at 11:16

Hi Lizzo,

Your link relates to men with 3Tb.

Unless I'm mistaken, I don't think we know what the original poster's cancer staging is.

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User
Posted 18 Apr 2024 at 19:04

Originally Posted by: Online Community Member

Hi can any of you share any research or studies regarding recurrence after RARP and radiotherapy.  Thanks 

Hello mate,

There's not much on your profile.

Do you mean what's the chances of recurrence following surgery compared to radiotherapy. Or do you mean, research into outcomes for those who've had surgery, recurrence and salvage RT?

User
Posted 18 Apr 2024 at 19:06

Here's an interesting one

https://community.prostatecanceruk.org/postmessage?t=30507&f=33

See in particular Figure 1 which shows the risk of recurrence, which is fairly high, but then also Figure 2 which shows how, for prostatectomy in particular, the risk of dying after recurrence is actually very low (4%-9%) at least up to 10 years after recurrence, which is actually quite a long time by cancer standards and also given the age of many men who experience recurrence.

User
Posted 18 Apr 2024 at 19:44

My apologies - the link in my previous post should be this one.

 

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2809152

 

User
Posted 18 Apr 2024 at 21:03

Hi KS25,

The link you give majors on Mortality after Prostatectomy which the OP might have had in mind but didn't ask for. It's not necessarily the same as statistics for recurrence which is what he did ask for. An affected patient's interest is going to be how successful his individual treatment will be comparing here overall results for Prostatectomy and Radiotherapy. This is too simplistic to be of much use because there are different ways of administering Surgery and Radiation. Also, some surgeons want to select only those cases where there is a good chance of success, thereby enhancing their reputations and leaving more doubtful cases for RT

These graphs are based on the analysis of many studies for various treatments and ellipses give a general idea of men considered low, medium and high risk with the compared treatments. This provides a general guide but it does show that some men do well or even better than those in a generally more successful group and there are many reasons why this can happen. Work your way round this site which considered 129,000 men. https://www.prostatecancerfree.org/compare-prostate-cancer-treatments/

 

Edited by member 18 Apr 2024 at 21:03  | Reason: to highlight link

Barry
User
Posted 19 Apr 2024 at 11:10

There is an abundance of studies on the Internet this study is on outcome for staging of t3b my husband was t3

I will try to post more studies later but it would help to know your psa gleason score and staging 

https://onlinelibrary.wiley.com/doi/10.1111/iju.14799

 

Edited by member 19 Apr 2024 at 11:16  | Reason: Add more info

User
Posted 19 Apr 2024 at 11:16

Hi Lizzo,

Your link relates to men with 3Tb.

Unless I'm mistaken, I don't think we know what the original poster's cancer staging is.

User
Posted 19 Apr 2024 at 11:19

Originally Posted by: Online Community Member

Hi Lizzo,

Your link relates to men with 3Tb.

Unless I'm mistaken, I don't think we know what the original poster's cancer staging is.

Exactly - I edited my reply just before I read your post 

 

 

Edited by member 19 Apr 2024 at 11:48  | Reason: Grammer mistake

User
Posted 19 Apr 2024 at 11:33

Newly diagnosed G 7  3+4 localised.. Just trying to see which procedure has least chance of recurrence 

User
Posted 19 Apr 2024 at 11:43

Thanks for the additional information Whitey but do you have your staging (T number).

User
Posted 19 Apr 2024 at 12:00

I haven't been given that , the consultant was very quick to had me over to the nurse , just said it was contained . I've got my first appointment with the surgeon on Monday . So I'm just formulating my questions 

User
Posted 19 Apr 2024 at 20:23

If it is described as contained then it's probably a T2 which is good news. If the cat is still in the bag then it reduces the risk of recurrence compared to a T3 where it is starting to break out of the capsule. Deciding on which radicle treatment to opt for is a complex and difficult decision as there is no obvious answer. I believe success rates for both surgery and radiotherapy are about the same. There are a lot of threads on this site discussing this very issue which you should find helpful.

 
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