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stereotactic radiotherapy

User
Posted 25 Nov 2025 at 18:26

Has anybody here had stereotactic radiotherapy as the primary treatment for PCa and can advise their experience and what short and long term side effects they may have had?

User
Posted 26 Nov 2025 at 00:31

Hi, rudge.


There are a few on the forum who've had SBRT. 


Recent American research shows:


For patients with intermediate-risk, localized prostate cancer, radiation therapy delivered in five sessions reduced patient-reported side effects compared to longer courses of radiation, according to results of a large, randomized phase III trial. Patients treated with stereotactic body radiation therapy (SBRT) reported fewer declines in bowel, urinary and sexual functioning but were more likely to experience a rise in prostate-specific antigen


https://www.astro.org/news-and-publications/news-and-media-center/news-releases/2025/shorter-radiation-improves-patient-experience-but-not-disease-control-for-intermediate-risk-prostate


Good luck, mate. 👍


 

Edited by member 26 Nov 2025 at 00:34  | Reason: Add link

User
Posted 27 Nov 2025 at 13:48

Thanks for the reply and links.

User
Posted 27 Mar 2026 at 20:41

Little bit late in posting.  I had the 5 day SBRT course at Barts around 12 months ago.  Aged 58 at the time.  The consultants advised that the outcomes were pretty much the same as surgery or longer period radiotherapy.  You have to be able to pee at a certain rate to qualify and the cancer has to be in specific places.  Great advantage of it is that its only 5 consecutive days perhaps broken by the weekend. Ten minutes or so a session.  For me, very little side effects at the time or later. Peeing more in the night mainly.  Gleason was 3+4.  PSA down from 17 to 2 in 12 months so all good.  Would recommend if available in your area and you fit with it. 

Edited by member 27 Mar 2026 at 20:48  | Reason: Not specified

User
Posted 28 Mar 2026 at 16:37
Thanks for the reply.

I underwent SBRT on 12h Jan 26 with 5 fractions over alternative days, so had last one on Wed 21st.

Had 1st PSA done at 6 weeks post treatment , with it only falling from 4.69 to 4.09, a 12% drop which I was a bit concerned about as most literature available indicates a 40% to 50% drop over that time?

PSA was repeated two weeks later a couple of days before seeing the consultant for the first time at 2 month post treatment and it had fallen to 2.69, so very happy to have seen such a quick fall from 4.09 o 2.69 in just 2 weeks.

Was originally on AS for 10yrs with a G6, 3 + 3 but last autumn following a MRI scan and bi-ops it had risen to a G7, 3+4 3 with 8% G4 so it was decided that I should go for treatment which after looking at all the options decided that SBRT was the one I would go for as the treatment was local to me.

Had flow test before treatment which was around 16ml/sec fairly good, but after the 2nd fraction I had to start on Tamsulin due to the swelling and inflammation caused by the radiation. Was then getting up around 7 times a night and after the last.5th fraction, ALL the side effects kicked in, which was not very pleasant.

However, after around 3 weeks post treatment these all more or less subsided and back to just getting up once a night.

I continued with the Tamsulin for a month post treatment and slowly reduced to every other day, and stopped taken them at around 2 months post treatment.

Currently I have no side effects to speak off, so very happy with the outcome though with radiation symptoms can come back at a later time.

Will have PSA and follow up with consultant at 6 months.
User
Posted 28 Mar 2026 at 16:53

Thank you.  That’s excellent outcome in the end so far! Good news.  I do recall that my PSA did take a few weeks to start properly reducing and like yours it was the second test where the big drop started.  Hopefully you continue on this path.


No particular side effects for me 12 months on except as mentioned up twice a night - but a small price to pay. 

 
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