Zoladex and Prostap are different drugs but work the same way i.e. to lower testosterone. The cost is similar for both although Prostap can be easier to administer. The drugs themselves do not directly fight the cancer - it's their action in creating a castrate level of testosterone that "starves" the PCa of the fuel it needs. Occasionally these drugs (known as LHRH analogues) do not do a 100% job and some testosterone remains. It is always a good idea to ascertain your testosterone level before concluding that whatever LHRH you are on has failed. Anything over 1.0 nMol/l is not really good enough and preferably lower. I struggled to get own testosterone down and it was only the addition of a steroid, Dexamethasone, that did it for me. The adrenal glands produce as much as 5 to 10% of body testosterone and are mainly unaffected by Zoladex or Prostap but low dose (0.5 to 2.0 mg) Dexamethasone can correct this. Other standard treatments are to add in 50mg of Casodex to "mop up" (hide) any remaining low levels of testosterone. Get the level tested - it's like driving a car with no speedo otherwise! http://community.prostatecanceruk.org/editors/tiny_mce/plugins/emoticons/img/smiley-laughing.gif
Edited by member 12 Aug 2014 at 20:31 | Reason: Not specified
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