Hi
My husband had Abiritone as part of a trial last year. Worked well for 4 months then liver functions went wild, ALT kept climbing, over a thousand (required hospital admission) but did come down eventually without further treatment. PSA had been responding well. As this was part of a trial he was then able to go onto Enzulutamide which he is now on - 5 months now. Both treatments seemed to work and he has been incredibly well with both.