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Caverject trial

User
Posted 20 Jul 2022 at 12:39

Yesterday I had a trial with Caverject at the hospital.  The injection itself was not too bad but the sheer agony of the resultant erection was unbelievable.  It felt as if my penis had been plugged into an air compressor.  Eventually after a couple of hours and a couple of Solpadeine the erection subsided but I limped out of there like John Wayne and went straight for a well deserved beer to settle the nerves.  The dosage given was 10mg and the consultant said I could try again but maybe with 2.5mg to see how that goes.  The physical erection was really good so I am tempted to try again with pain killers close at hand.


Had anyone had success with Caverject?  Does lowering the dosage reduce the pain?  Does the pain reduce after the first few attempts?  Any thoughts?  


 

User
Posted 20 Jul 2022 at 14:47

I shouldn't be replying as I know very little about this and although I have a lot of ED I wouldn't stick a needle in.


I have read that if you use too much of some treatments it can cause far too great an erection that can last for hours and be painful.  Don't take my word but taking the smallest dose initially sounds a good strategy. 


I'm sure there's something on this site about that if you search perhaps using Caverjet.

User
Posted 20 Jul 2022 at 15:36

Hi Jellies, 


I use Caverject but have never used more than 2.5 mg.


My first injection was carried out by the ED nurse to test for any adverse reaction. Her advice was to start with the minimum dose. I did get some throbbing pain on the first few injections but not now, I put that down to not having a proper erection since the night before my prostatectomy over a year earlier, despite using a pump regularly. 


I think it's worth having another go but with 2.5 mg. Then if that's still unbearable, it's worth trying invacorp, some guys on here swear by it but supplies can be like rocking horse poo.


I found injections well worth it, they gave me a huge mental boost, a lot of fun and formed an important part of my recovery. 


Hope this helps.


Kev.

Edited by member 20 Jul 2022 at 15:59  | Reason: Typo

User
Posted 20 Jul 2022 at 16:13

Not that I know anything about injectables, but I did hear that some ED specialists start at the highest dose and work down rather than the more conventional approach with medicine of lowest dose and work up.


The logic behind this is that a man can get pretty disillusioned if the medication doesn't appear to be effective straight away. So it sounds like 10mg might be the highest dose and they will almost certainly take this right down as it was too effective.

Dave

User
Posted 20 Jul 2022 at 17:10
10mg turned me into a coat rack for about 2 hours, 2.5 used to work well for me (partial nerve sparing but no erections for 12 months when I first tried it). Still had to walk up and down stairs to get it to go down!

Never painful for me or maybe I just enjoyed the throbbing sensation!

2.5 is a tiny amount though so you have to get the technique right..
User
Posted 20 Jul 2022 at 19:38
Caverject was a no-no all those years ago. Tried twice with only semi-erection but felt like it had been slammed in a car door. Moved onto Invicorp25 injections. Full lob and zero pain. Thankfully now I don’t need injections.
Good luck.
User
Posted 20 Jul 2022 at 20:22

My first dose was 2.5 in the clinic then tried 2.5 at home and reported back that it was OK but glans didn't swell.
Nurse said try 5mg next. So,I tried 5mg and had a six hour hard on from hell. Nurse said back to 2.5 so tried again and OMG 9 hours before it went down after sudafed, running cross trainer etc.
Just a word of warning after four hours you should go to A and E because severe damage can be done. I didn't because of alcohol and no transport and got away with it but after nine hours that was just lucky but stupid.
Needless to say no more caverject for me!


Cheers
Bill

User
Posted 21 Jul 2022 at 18:32

Try the lower doses by all means but invicorp 25 was totally pain free.  I don't think it's available in all areas.

User
Posted 15 Aug 2022 at 21:48

Great update Jellies, glad that your perseverance is paying off and you're having some well deserved fun.


Injections make for weird foreplay but they're definitely worth the effort. 


Happy days!


Kev.

User
Posted 12 Nov 2022 at 15:42

Brecon99 - For me the male urologist showed me how to use the injection and he did the first one.   We had a laugh and said if we ever meet on the street it didn't happen.  I'm sure if you want a male doctor/nurse you should be able to request that.   They did not "inspect" anything afterwards as it was not necessary because I could just tell them how it felt.  I hate needles so afterwards when I went home I said to myself that I would try 10 times and after that determine if I would continue or not.   It took me about 5 times to dial in the dose which I did myself and I find if I use too high a dose it is very painful for about 2 hours afterwards. It also took a few times to mentally get used to handling the needles. The injections are far from perfect but I am very thankful for them as nothing else works for me either. Best wishes. 

User
Posted 12 Nov 2022 at 16:28
In our area, both ED nurses are female. I don't think it has ever bothered John - he was more concerned about regaining erections than about the gender of the person providing him with the help he needed. At the first appointment, she talked to us about our sex life and what we had already tried, showed us both how to prep the injection and then took John behind a curtain. She did the first injection and like CC, we waited in the clinic for a short while before going back in to let her know whether it had worked. I don't think she looked at the erection. On subsequent appointments, we talked about success / difficulties / dosage but she never needed to look at his penis again.

Women don't usually get a say in the gender of the medical professional working with them unless they are the victim of a sexual crime - my gynaecologist was male, it was a man who removed my breast and I once had a male midwife. My GP is also male.
"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard
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User
Posted 20 Jul 2022 at 14:47

I shouldn't be replying as I know very little about this and although I have a lot of ED I wouldn't stick a needle in.


I have read that if you use too much of some treatments it can cause far too great an erection that can last for hours and be painful.  Don't take my word but taking the smallest dose initially sounds a good strategy. 


I'm sure there's something on this site about that if you search perhaps using Caverjet.

User
Posted 20 Jul 2022 at 15:36

Hi Jellies, 


I use Caverject but have never used more than 2.5 mg.


My first injection was carried out by the ED nurse to test for any adverse reaction. Her advice was to start with the minimum dose. I did get some throbbing pain on the first few injections but not now, I put that down to not having a proper erection since the night before my prostatectomy over a year earlier, despite using a pump regularly. 


I think it's worth having another go but with 2.5 mg. Then if that's still unbearable, it's worth trying invacorp, some guys on here swear by it but supplies can be like rocking horse poo.


I found injections well worth it, they gave me a huge mental boost, a lot of fun and formed an important part of my recovery. 


Hope this helps.


Kev.

Edited by member 20 Jul 2022 at 15:59  | Reason: Typo

User
Posted 20 Jul 2022 at 16:13

Not that I know anything about injectables, but I did hear that some ED specialists start at the highest dose and work down rather than the more conventional approach with medicine of lowest dose and work up.


The logic behind this is that a man can get pretty disillusioned if the medication doesn't appear to be effective straight away. So it sounds like 10mg might be the highest dose and they will almost certainly take this right down as it was too effective.

Dave

User
Posted 20 Jul 2022 at 17:10
10mg turned me into a coat rack for about 2 hours, 2.5 used to work well for me (partial nerve sparing but no erections for 12 months when I first tried it). Still had to walk up and down stairs to get it to go down!

Never painful for me or maybe I just enjoyed the throbbing sensation!

2.5 is a tiny amount though so you have to get the technique right..
User
Posted 20 Jul 2022 at 19:38
Caverject was a no-no all those years ago. Tried twice with only semi-erection but felt like it had been slammed in a car door. Moved onto Invicorp25 injections. Full lob and zero pain. Thankfully now I don’t need injections.
Good luck.
User
Posted 20 Jul 2022 at 20:22

My first dose was 2.5 in the clinic then tried 2.5 at home and reported back that it was OK but glans didn't swell.
Nurse said try 5mg next. So,I tried 5mg and had a six hour hard on from hell. Nurse said back to 2.5 so tried again and OMG 9 hours before it went down after sudafed, running cross trainer etc.
Just a word of warning after four hours you should go to A and E because severe damage can be done. I didn't because of alcohol and no transport and got away with it but after nine hours that was just lucky but stupid.
Needless to say no more caverject for me!


Cheers
Bill

User
Posted 21 Jul 2022 at 18:32

Try the lower doses by all means but invicorp 25 was totally pain free.  I don't think it's available in all areas.

User
Posted 21 Jul 2022 at 21:57

Originally Posted by: Online Community Member
Not that I know anything about injectables, but I did hear that some ED specialists start at the highest dose and work down rather than the more conventional approach with medicine of lowest dose and work up.


That's done for the PDE5 inhibitor tablets, but I don't think it would be a good idea for the injections.

User
Posted 21 Jul 2022 at 22:02

Originally Posted by: Online Community Member
My first dose was 2.5 in the clinic then tried 2.5 at home and reported back that it was OK but glans didn't swell.


The glans is on a different blood supply from the corpus cavernosum (main erectile part).


The glans blood is supplied by the corpus spongiosum, which is a small erectile tissue around the urethra, and forming the penile bulb in the perineum. The injection wouldn't normally go in to this.

User
Posted 23 Jul 2022 at 15:53

Thanks all for the info and suggestions.  I'll try the 2.5mg dose instead with Solpadeine and Sudafed at the ready. The pharmacy confirmed that Invicorp is not available here in Ireland (presumably not licensed).  Also for Caverject only the vials are available on the drug purchase scheme, not the dual chamber system.  In Ireland you pay the first 80euro per family per month for prescriptions and after that it is covered, but there is no particular limit on the amount of Caverject vials you can get within reason.

User
Posted 15 Aug 2022 at 13:11

Just to update on this... 


I got 10 units from the pharmacy and so far have used about 5.  Public health here covers 12 units per month for a capped fee but we can only get Caverject,  not Invicorp.  


The injection process itself is not too bad.   You do get used to it and can come quite proficient.  I am not a fan of needles so for anyone on the fence I would not let this stop you trying.  Another benefit of injections is that they draw new blood into your penis which is good for penile health. 


After my hospital experience I started with a really low dosage of 1.25mg.  This gave me a semi which was usable but not great.   


Then I upped it to just under 2.5mg which was pretty good with not too much pain afterwards. 


Feeling confident I then upped it to 3mg which was rock hard but left me with a 2 hour erection doing jumping jacks in the kitchen at 1am.  It also caused a lot of pain requiring pain killers. I was surprised that the response between 2.5 and 3 was so sensitive.  However with a stronger erection I was able to get a better orgasm so it is a trade off.   It also gave me a lesson to only test higher doses during the day to allow recovery time in case it is too much.   2.5mg looks like the ideal zone for myself but this seems to be very variable between individuals. 


A disadvantage with injections is lack of spontaneity.   But as a married man that is not a problem and my wife has bought into the twice a week regime. The experience itself has actually been quite good even though still early days.  


Next steps for me is to continue dialling in the dose.   Would consider a mini fridge for the bedroom to have some preprepped injections ready to go.  Also Invicorp seems to be a magical elixir so might see if somehow I can use some contacts to get some from up the road Belfast. 


Just wanted to share in case anyone else in the same boat and considering injections.  

User
Posted 15 Aug 2022 at 21:48

Great update Jellies, glad that your perseverance is paying off and you're having some well deserved fun.


Injections make for weird foreplay but they're definitely worth the effort. 


Happy days!


Kev.

User
Posted 12 Nov 2022 at 10:05

The following few replies may not make sense as the member as deleted his post and changed  his name.


 


 


Brecon,there are a few guys on here who use the injections and have more experience than me. I was offered the injections and pump at my first meeting with my ED guy. I declined the injections in favour of Muse. With muse you put a thin applicator down the eye of the penis, not as bad as it sounds. It was hit and miss so eventually I decided on trying the injections. 


 


At the first appointment the urology technician explained and showed me how the mechanics of the syringe worked and explained how to prep it and where precisely to inject it. The actual needle is very thin. Then it was trousers and pants down and under her instructions I injected the penis. After getting dressed I then waited in the waiting room for about 20 minutes, I then returned to see the technician for an inspection, there was some swelling but not a great deal. I refer to her as a technician because she is more than a nurse but not a doctor, she also performs biopsies. She was very professional and there was no feeling of embarrassment on my part. After eight years if being poked and prodded I don't get embarrassed any more 


 


Back at home a few days later i tried again and got a really good swelling, which was put to good use. As i said before I do have to get my head around doing the injection, perhaps the more I do the injections the less it will bother me. 


The dose is selected with a dial on the syringe, it is a bit trial and error. Sometimes the injection may not work because it is in the wrong place and there have been reports of faulty batches. I was told multiple injections was a no no. 


We all have different experiences and conditions, I find stimulation helps get me a bigger swelling. 


If the erection lasts too long you need to get medical help. Hope all goes well.


 


Thanks Chris 

Edited by member 14 Nov 2022 at 17:58  | Reason: Clarification

User
Posted 12 Nov 2022 at 11:51

Brecon, our ED clinic is led by a male consultant but not sure if he does the injection tutorials. The pump rep is male but ours did not carry out any intimate instructions.  I have found that 95 percent of urology staff are female and like wise with district nurses who change my catheter.


Thanks Chris 

User
Posted 12 Nov 2022 at 15:42

Brecon99 - For me the male urologist showed me how to use the injection and he did the first one.   We had a laugh and said if we ever meet on the street it didn't happen.  I'm sure if you want a male doctor/nurse you should be able to request that.   They did not "inspect" anything afterwards as it was not necessary because I could just tell them how it felt.  I hate needles so afterwards when I went home I said to myself that I would try 10 times and after that determine if I would continue or not.   It took me about 5 times to dial in the dose which I did myself and I find if I use too high a dose it is very painful for about 2 hours afterwards. It also took a few times to mentally get used to handling the needles. The injections are far from perfect but I am very thankful for them as nothing else works for me either. Best wishes. 

User
Posted 12 Nov 2022 at 16:28
In our area, both ED nurses are female. I don't think it has ever bothered John - he was more concerned about regaining erections than about the gender of the person providing him with the help he needed. At the first appointment, she talked to us about our sex life and what we had already tried, showed us both how to prep the injection and then took John behind a curtain. She did the first injection and like CC, we waited in the clinic for a short while before going back in to let her know whether it had worked. I don't think she looked at the erection. On subsequent appointments, we talked about success / difficulties / dosage but she never needed to look at his penis again.

Women don't usually get a say in the gender of the medical professional working with them unless they are the victim of a sexual crime - my gynaecologist was male, it was a man who removed my breast and I once had a male midwife. My GP is also male.
"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard
User
Posted 12 Nov 2022 at 20:31

I've just started on Viridal Duo (which is Alprostadil, but I'm not sure if it's exactly the same as Caverject?).  I was given 5mcg. by the E.D. Nurse, which provided a reasonable erection, but was not rock solid.  They advised trying 10mcg. at home.  This gave me a rock solid erection, but it was extremely sensitive to touch.  I tried to masturbate very gently, which was just about possible, but I imagine that penetration would have been impossible due to the pain.   I ached for a couple of hours afterwards, but it did ease off and I didn't have any problem with an erection that wouldn't go down. I might try 7.5mcg. next time.


I also bought some Invicorp from a private clinic, just to test it out.  It was £100 for 5 shots, so £20 a shot - not something I could afford too often.   There was absolutely no pain, but the erection was quite a sad-looking thing.  The 5mcg. of Viridal Duo given by the E.D. Nurse gave better results and was free on the NHS.


I wonder if anybody has used a vacuum pump to get them started, and then injected themselves?  If so, did the combination give better results?


This seems to be a trial-and-error process.  As others have said, every individual seems to have a different response.


 

User
Posted 12 Nov 2022 at 20:52

I use just under 2.5mcg of Caverject.  If I go even a smidge above 2.5mcg I get a rock hard erection followed by 2 hours of agony.  But if I go too low the erection is a bit sad.   So for me it was a matter of finding the goldilocks zone where it is "just right".  It can take a bit of trial and error to get there. 

User
Posted 13 Nov 2022 at 00:58

You don't usually see a urologist about ED; you see a specially trained nurse. These are rarely available privately. The vast majority of ED nurses are female. Clearly you feel very strongly about this but I don't think you can speak for the majority of men - I have been on this forum for 12 years and can only recall a couple of men who posted about being really uncomfortable about seeing a woman.


In our case, it worked out well because our ED nurse was skilled and sensitive; she was a great support to both of us. I hope that you find your local andrology clinic does have male staff.

Edited by member 13 Nov 2022 at 01:00  | Reason: Not specified

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard
User
Posted 13 Nov 2022 at 11:13

You seem very angry. I tried to give you some helpful information, that's all. 


It might be better to start your own thread rather than taking someone else's in a different direction  

Edited by member 13 Nov 2022 at 11:16  | Reason: Not specified

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard
User
Posted 13 Nov 2022 at 13:49

Brecon, you can ask the moderators to split the post, or I can request it for you. 


Contacting the moderators


onlinecommunity@prostatecanceruk.org.


To expand in my previous answer , my first post op meeting with the ED department was with the male consultant and male pump rep. 


For my second visit many years later to talk about injections I was expecting to see the male consultant but because I had already seen him and he was running late, I was seen by the female urology technician. I assume she probably had to get the prescription approved by the consultant.


There are members of my hospital and doctors surgery that I refuse to see but that is because I dislike or don't trust them, not because of their gender.


I really hope you find a resolution and get the caverject, it will be worth it. This disease is bad enough to deal with without additional problems.


Thanks Chris 


 


 

 
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