Hi PN,
Biopsy results will be carefully assessed and reviewed by a Multi Disciplinary Team and considered along with scans and a diagnosis given. Should his result be positive he will given a grade for his cancer and a staging which says how much cancer is there, it's location and whether it is believed to be still well contained within the Prostate. The patient is then advised of treatment options. It is usual for Prostates to grow with age but some do so excessively and produce greater levels of PSA, which could be at least part of the reason why PSA is above range for age. The shadows on MRI are of concern but do not confirm PCa, hence sample cores are taken that can be examined in the lab. Even if it is shown to be cancer, it could be that it is not essential to treat it unless it or the enlarged size are thought to be affecting the passing of urine which might have been why he was given a PSA test in the first place. By your husband's age about half of men will have some cancer in their Prostate, so vast majority whether treated or untreated go on to die of something else. Of course where the cancer is significant , found early and treated, their long term survival chances are improved.