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The million dollar question

User
Posted 24 Oct 2025 at 15:33
Hi Phil,
Sending a little encouragement your way, as the first clinical results from the Halda trials were announced today. I hope the pain is now being suitably managed and that you’re holding up alright. Wishing you all the very best for Monday!
User
Posted 24 Oct 2025 at 17:53

Totally agree. The early trial results look very promising, especially at the 25 mg and 50 mg doses which I think is what they're testing moving forward. The 50 mg group had a 70% rate for PSA halving (or better) and 40% of them saw their PSA fall over 90%. That is obviously a very small sample size - but it's a success rate that is about twice as good as Cabazitaxel and also better than Lutetium-177, if those results are repeated. 


So that's positive news, probably explains why the Marsden people were optimistic, and with good resson. You're in very good hands, Phil. 


We have a consultation for my father next Friday with his oncologist to discuss trials. Do you happen to know if they're still accepting patients for this trial at the Marsden? We're looking at this one and the PAnTHA one at UCLH for Actinium-225 - given Lutetium-177 didn't make a dent in my father's disease, this trial could be a better option if it's still possible to get him into it. Weirdly there's nothing online about this trial coming to the UK, it's all about the US. I might enquire with the oncologist next week.

User
Posted 25 Oct 2025 at 09:05

Hi guys


Thanks for your responses


Yes have looked at feedback from early results from trial and it looks promising.


Pain from lower back and rib area are under control with stronger pain killers but QOL is still ok.


Blood tests and consultation monday and take the magic tablet Tuesday morning🤞


Unfortunately I think the window for signing up for this trial is closed but they've always got trials in mind.


Best wishes phil 

 
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