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The million dollar question

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User
Posted 11 Dec 2025 at 19:53
Brilliant news. Hope you get to have a lovely Christmas and fingers crossed the scans in Jan evidence the drop in PSA.
User
Posted 11 Dec 2025 at 21:04

Phil, that's absolutely bl00dy fantastic news. Psa going down amazingly and aches and pains reducing. 

What a wonderful Christmas gift for you, couldn't be happier for you both. 

Melissa x

Edited by member 11 Dec 2025 at 21:07  | Reason: Not specified

Mrs MAS

User
Posted 12 Dec 2025 at 08:16
Brilliant news Phil, best Christmas present this year. So good to hear that it is doing the job for you.
User
Posted 12 Dec 2025 at 08:45

Great news Phil, looks like things are going in the right direction.

Thanks Chris 

User
Posted 12 Dec 2025 at 14:12
Wow sounds like whoever invented this targeted chemo is really on to something.....
User
Posted 13 Dec 2025 at 07:47

Great news Phil long may it continue, hope you and you family have a wonderful Christmas 

Ann

User
Posted 13 Dec 2025 at 11:08

Really pleased to see this Phil, long may it continue.

Leila 

User
Posted 13 Dec 2025 at 11:17

Thanks all for your replies and best wishes,don't know how long this drug will last but make hay while the sun shines.

Probably won't post again this side of Xmas so Wishing you all a good one.🤶 

Regards Phil 

User
Posted 14 Dec 2025 at 07:54

Phil it's great news again and you've achieved an almost 90% PSA reduction over the 3 results.

Enjoy Christmas with renewed hope, as I and many others will too!

User
Posted 01 Jan 2026 at 09:18

Hi all and happy new year

Little update,started cycle 4 Tuesday(21 day cycle)of Halda phase 1 trial.

Hospital visits will not be as intense now (every 3 weeks) PSA down again to 29,that may seem high to sone people but for me its the lowest its been for over 12 months,no real side effects to report and QOL good.1st x=ray,mri & ct booked in for next week.

Will keep you updated as always regards Phil 

 

User
Posted 01 Jan 2026 at 09:40
So glad you’ve been able to feel good this Christmas and New Year Phil. Fingers crossed for you!
User
Posted 01 Jan 2026 at 09:43
All the best for New year Phil and family, hope you all had a great Christmas, thanks for the updates, everything crossed for your PSA to keep falling
User
Posted 01 Jan 2026 at 09:45

Hi Phil,

Another brilliant result, mate. Long may they continue. A great start to 2026. Good luck with your X-ray and scan. 👍

 

User
Posted 01 Jan 2026 at 10:06

Agreed - superb result and very encouraging.  Keep it up!  Happy and healthy 2026 all.  

User
Posted 01 Jan 2026 at 12:34

What a great start to the new year Phil, your psa has taken a battering whilst on Halda trial and I'm so very pleased for you. 

I look forward to more good news after your scans. This treatment feels like a game changer. Fabulous.

X 

 

Mrs MAS

User
Posted 01 Jan 2026 at 15:57
Mate ❤️❤️❤️
User
Posted 01 Jan 2026 at 18:11
I don’t understand this reliance on PSA. My husband s was very low but the cancer spread to the liver and he died
User
Posted 01 Jan 2026 at 18:21
Jimthecobowner, for the majority of Prostate cancers PSA is directly proportional to the amount of active tumour, so the lower it goes following treatment the better.

Unfortunately some Prostate cancers produce very little or no PSA, it sounds like your husband was unfortunately one of those types. Condolences on your loss.

User
Posted 02 Jan 2026 at 09:50

Hi francij 

Thanks for the intel I didn't know that and it makes sense with the cancer showing on my spine in my last images about 3 months ago.

Cheers pal 

 

User
Posted 02 Jan 2026 at 10:32
thanks for explanation, my PSA when diagnosed was only 20.1 my Oncologist keep saying that PSA is only an headline we look at all the blood test results to see what's going on
User
Posted 19 Jan 2026 at 17:27

Hi all its update time.

Had bloods tests,results of recent imaging and consultation today.

PSA down again to 23,tumours to lower back,rib and lymph node pressing on urethra reduced,cholesterol still high so statin dosage increased,tumour to neck region no change,but consultation pleased with my response so start cycle 5 of phase 1 halda clinical trial tomorrow morning.

Still aching neck/shoulders,headaches not so bad,hot flushes have increased but QOL still good next visit to royal marsden in 3 weeks for cycle 6.

Wishing you all the best on your journeys.

Stay strong 💪 regards Phil.

User
Posted 19 Jan 2026 at 17:36
Respect Phil as always 🙏🙏 and you’re a true fighter
User
Posted 19 Jan 2026 at 17:38

Phil, good to hear things are going in the right direction.

Thanks Chris 

User
Posted 19 Jan 2026 at 17:50

Hey Phil

Ive been watching for your update. This is superb!

I am so very pleased for you. 

Keep going!

Love Mrs MAS x

Mrs MAS

User
Posted 19 Jan 2026 at 18:15

Originally Posted by: Online Community Member
QOL still good next visit to royal marsden in 3 weeks for cycle 6.

Hi, Phil.

Thanks for the update, mate. I'm very glad that you're feeling okay and that the treatment is proving effective. I hope the next cycle is as successful. Good luck.👍

User
Posted 19 Jan 2026 at 20:06
Thanks so much Phil. so happy to that this seems to be improving things or holding at bay and that QOL is ok. Hoping for the best for the next cycle.
User
Posted 19 Jan 2026 at 20:47
Thanks for the great update Phil, glad it is doing its job and your feeling ok. Wishing all the best for the next couple of rounds.
User
Posted 19 Jan 2026 at 21:01

Great news Phil. 

Best of luck for cycle 6.

Kev.

User
Posted 20 Jan 2026 at 17:18

Thankyou all from me and my wife for all your kind thoughts & messages.

Will update as always in a few weeks

Regards Phil 

User
Posted 10 Feb 2026 at 11:00

Hi Guys its update time.Hope you are all as well as you can be.

Starting cycle 6 of the phase 1/2 clinical trial PSA still going down now its 20,cholesterol has gone down but remaining on statins other side effects minimal and QOL good,next imaging in 3 weeks when I start cycle 7 and as always will update then.

Stay strong 💪 everyone

Phil 

User
Posted 10 Feb 2026 at 11:14

Hi Phil,

I have been watching for your update and delighted that your PSA is still going down and you are doing well! Just want to give you a big hug! x

Mrs MAS

User
Posted 10 Feb 2026 at 12:20

Hi Phil,

So good to hear from you. I have also been thinking of you, and watching for your post. Glad to hear PSA still declining and QOL still good. Wishing you the best. Hugs to you, your family (and to Mrs MAS as well).

User
Posted 10 Feb 2026 at 13:15

Great news Phil, 

Hopefully you breeze your treatment and that your PSA continues to fall. 

Good luck, 

Kev.

User
Posted 10 Feb 2026 at 13:53
Great to hear from you and your QOL.

Lion-king Phil 🙏

User
Posted 10 Feb 2026 at 18:33
Great stuff
User
Posted 10 Feb 2026 at 22:20

Great news, Just keep on marching. Take care 

User
Posted 12 Feb 2026 at 09:08

Hi all

Yet again thanks for all your kind thoughts and support,will update when needed and keep a close eye on all your journeys 

Regards Phil 

User
Posted 12 Feb 2026 at 19:34

Loving this

User
Posted 05 Mar 2026 at 08:39

Hi Guys....update time

After consultation,bloodtests and imaging earlier this week,PSA is down again to 16 cholesterol down and stable but remain on statins,QOL life good.

On the down side after mentioning mark on head was told bluntly by consultant that it was skin cancer! But my local GP begs to differ and have been given antibiotic cream and an appointment for next week at a local health Centre for further investigations.

Will update on skin cancer investigation and imaging results in the next few weeks.

All the best everyone and stay strong 💪 

User
Posted 05 Mar 2026 at 08:45

Hi Phil, 

Great news on your PSA and your good QoL, long may it continue. 

Good luck with the skin tests 🤞🏻

Cheers, 

Kev.

User
Posted 05 Mar 2026 at 09:05

Bloody hell Phil, I am over the moon for you. This trial feels like a miracle treatment to me. 

Hope the skin thing is treatable for you. 

But wow, you have kicked the PSA right down. Good man

X 

Mrs MAS

User
Posted 05 Mar 2026 at 09:55

Great news Phil! There was something in the news about a new drug that is working wonders for men with advanced PC. Things are looking more optimistic thankfully. Hope the skin lesion is nothing to worry about. 
Good luck!

Linda

User
Posted 05 Mar 2026 at 11:55
Ditto from me! Really glad to read these news. It's so great that the incredible enthusiasm for HLD-0915 seems to apply to you. I was reading more about this new type of medicine. Really hope it works as they plan and truly kills off the recurrent/lingering/mutant PC. Big hopes with you. Long may it continue! And good luck with the patch on your skin. My fingers are crossed for you on that also.
User
Posted 05 Mar 2026 at 14:46
Really glad to hear this Phil. I’ve been called in for bone and ct scans and an appt 2 weeks later. Scary stuff. Hoping this drug is a cure.
User
Posted 06 Mar 2026 at 10:42
fantastic news about your QOL, and PSA still falling, bugger about patch of skin needing follow up treatment, take care try to enjoy spring we woke up to a light covering of snow this morning its melted now, so our spring appears to be on hold

thanks for doing these updates

User
Posted 25 Mar 2026 at 15:22

Hi all

Update time again.

Started cycle 8 of Halda 0915 phase 1/2 Clinical trial yesterday.

Results from imaging good with no progression and reduction again in tumours,PSA down to 15 only down slightly this time but still good,QOL still ok but with slight back ache which I'll suck up.

Skin cancer to head was skin cancer but not bienin so had cryotheorpy on several marks on my bald head which made my eyes water but healing well.

I'll keep taking the tablets and live consultation to consultation,stay strong 💪 all and keep fighting the fight.

Regards Phil 

User
Posted 25 Mar 2026 at 16:11

Hi,  Good luck with the trial, I admire your fortitude. Looking up the trial it's beyond me and so is the summary.    The full description is linked here if anyone wants to look.  https://haldatx.com/wp-content/uploads/2025/10/AACR-Triple-Meeting-Halda-Presentation-24OCT2025-1.pdf

I've had 16yrs of various sun damage treatments on my scalp.   I went privately in November and was given cryotherapy. He said keep it covered in vaseline, don't puncture the blister.  It was great advice and healed very quickly without sign.   Although if it made your eyes water he might have given you a bigger blast.

All the best, Peter

 

User
Posted 25 Mar 2026 at 16:25

Dear Phil, So pleased that the trial goes well! Really excellent news! I have been following this trial (and others) but don't know when the next update will be. The first data release was outstanding and led to the small biotech that made it being purchased for 4 billion dollars. I hope that is a good sign. The drug works in a completely novel way. Wishing for the best.

And good luck with your scalp. I've been worrying about some spots on my husband. Must get those checked. Sorry this was eye-watering but hope for good healing. I've just had a friend go through it and in a week (and definitely by 2) it was much improved.

 

User
Posted 25 Mar 2026 at 16:34

Hi Phil

What a gift this trial is, the God's are shining down on you I think and I'm so pleased for you.

You could look upon the skin stuff as a distraction!

As always, I'm rooting for you. 

X

Mrs MAS

User
Posted 25 Mar 2026 at 17:02
Phil , stoked for you !! Bravest fighter ever. I was asking my Onco about Halda today. Apparently Abi only for me soon. Keep strong
 
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