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Posted 11 Sep 2017 at 12:44

I had radiotherapy for Prostate cancer 13 years ago  (I am now 68) and all has been well with PSA levels down to almost zero. I even forgot to have my PSA checked last year, it just never entered my mind. I had a blood test a couple of weeks ago for something else and asked them to do a PSA one too, which they did.  The result showed an increase from near zero to 4.7. I have no infection that i know of or any other pains. Anyone able to advise on what is happening? 

Posted 11 Sep 2017 at 14:08

Hello Davee

I can't be of much help with your question but I'm sure that others will advise you.

You say you have no infection that you know of but is that based on how you feel as I assume that the GP has checked you for infection

Has your GP referred you back to the hospital?

We can't control the winds - but we can adjust our sails
Posted 11 Sep 2017 at 16:48
I would suggest that you see your g.p and ask that he/she refer you back to the hospital for further tests and checks. Good luck
Posted 14 Sep 2017 at 10:38

Hi Davee,

As others have pointed out, one test alone doesn't prove anything, I guess further tests/scans etc may be needed.

I see like me you had radiotherapy some years ago, I guess you were told at the time that you could only ever have one bout of radiotherapy.  If it worked it worked, if not then it was hormone therapy for the rest of your life?

That has changed, if you check my profile there are all the details of salvage HDR brachytherapy.  'Fingers crossed' it is working for me, and even if it is not it is buying me a lot of time with my PSA bumping along at currently a mere 0.5

So hopefully you don't have a reoccurrence, but if you do please be aware that science has moved on and new treatments are available.



Posted 18 Sep 2017 at 11:39

Thank you for that info Dave and Andrew. It was quite a shock as it had all gone out of my mind and didn't even have a PSA test last year. My readings were less than .1 five yrs ago but not bothered to check since. Just found out today that in 2015 it had doubled to 1.49. I was not informed of this!
Urine infection has been ruled out. So being referred to the local hospital in the normal 2 weeks.
Interested to hear about your experience Dave.

Posted 19 Sep 2017 at 09:48

Hello yes urine tests were neg. Referred to local hospital in next 2 weeks.

Posted 26 Oct 2017 at 11:43

Latest blood test is down to 4.3 from 4.7 ?? Urologist examined my prostate and commented that it was small He is deciding what to do. I have no symptoms at all. I have had bad Gout for last 2 years dont know if that can be connected?

Posted 26 Oct 2017 at 14:24

That's interesting Andrew. I have having Allopurinol for gout at 300mg rather than earlier 100mg daily for long before being diagnosed with PCa, so haven't checked the info literature that comes with it which presumably mentions this. Although my treating consultants should have been aware of this from my records, none of them mentioned it as a potential source for increasing PSA.

Posted 30 Oct 2017 at 11:57

I was told their decision re what they intend to do. They consider the PSA reading which is now 4.3 does not justify any immediate action. They have suggested if it reaches 10 then they will do a MRI scan. Im not happy about this as I shouldn't have a significant reading at all after having had Radical RT. It also appears the committee were not told I had had RT. :-(

Posted 30 Oct 2017 at 15:19

Davee, RT doesn't destroy the prostate, so you should still have a positive reading, close to normal, say 4 I reckon the advice you have been given is sound, subject to resolving the issue about your medication.


Posted 30 Oct 2017 at 15:23

Hi Davee


You mentioned you had a "Radical RT".....do you mean RP (radical prostatectomy)?

If you still have your prostate...then some PSA will still be detected and produced.

IF you had an RP...then I think ANY PSA would indicate Mets.


Edited by member 30 Oct 2017 at 15:25  | Reason: Not specified

Posted 30 Oct 2017 at 20:02

Bill, Daveee had radical RT - radical simply means that it was the primary treatment.

Davee, your prostate will have recovered somewhat and the healthy prostate cells will be generating PSA. The level has gone high enough to be concerned but you can't have any more RT so what would you want the doctors to offer you as a treatment? Hormone therapy would be long term now and does not last forever so perhaps the MDT are trying to delay starting HT for as long as they can? Have they said how high your PSA needs to go before they put you back on treatment?

"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

Posted 29 Nov 2019 at 13:19
Helllo, Im sorry I have not been on for a while. My PSA has been up and down the last 2 years and was at 7.24 in October 2019, (7,28 in October 2018). Just to confirm I had radiotherapy in 2004 when my PSA was 15. (Gleeson 5, T2 2 +3). The hospital say i should start Hormone treatment at PSA 10. However at 70 yrs of age and readings being so slow moving im hoping it wont be necessary.
Posted 11 Apr 2021 at 21:02
Mt PSA readings since I was told my pc had come back after 13 years.

Sep 2017 4.76

Oct 2017 4.37

Jan 2018 5.35

Apr 2018 5.90

July 2018 5.99

Oct 2018 7.28

Jan 2019 5.75

Apr 2019 6.31

Jul 2019 7.14

Oct 2019 7.24

Jan 2020 6.93

Jul 2020 7,53

Oct2020 6.26

Jan2021 7.13

Posted 12 Apr 2021 at 04:47
On the basis of your PSA record, it could still be 2 or 3 years or even longer before it reaches the arbitrary 10 figure given by your consultant. Your Jan 2021 figure is lower than the one in Oct 2018 so PSA is not 'taking off'. However, PSA figurers alone cannot be relied on completely. In your situation I would ask whether you could have a mpMRI to check on what might be happening. If thought advisable it might be suggested you then have a Biopsy and perhaps some focal therapy. This is what I had in 2015 when my PSA was lower than yours as HIFU as salvage treatment for failed RT. It did knock back the PSA but this has now increased and I am due to learn the result of my latest mpMRI this month. It's possible that I may be offered repeat HIFU, told I can start HT or wait another year for a further mpMRI or unusually high PSA figure. I have previously rejected further HT due the side effects I had with it in 2008 when I had it with my RT.


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