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My PSA

User
Posted 14 Jun 2026 at 22:32

Hi, I’m a 56 year old white male, I have a PSA 3.85, had a MRI done last week they have found 7mm area left hand side of prostate (indeterminate) been graded P-RAD 3 , prostate 34ml no spread out of prostate , psa density 0.11 now waiting for a biopsy and obviously worried anyone else had things similar, thanks.

User
Posted 15 Jun 2026 at 13:54

Hi.

The biopsy is had was not bad at all. It was transrectal rather than transperineal. 

Obviously that means the ultrasound probe and biopsy tool go up the rectum.

But transperineal still requires the ultrasound probe to go in via the rectum even though the biopsy needles go in from outside the body.

The man who went in before me was absolutely terrified, completely and utterly mortified about something going up his bottom. 

When he came out he was "What is all the fuss about, easy easy, didn't feel a thing" 

I was OK with the idea of the biopsy and it went really easily.  There is some discomfort sure, but id rather do that than have a tooth out.

Just relax and wait for each test and result to come along. 

Your results are way less than mine and I came back all clear. 

Best regards Mick 

User
Posted 16 Jul 2026 at 17:16

Hi Adrian, thanks for the reply, I think hopefully you’re right it’s just in the area which is not to far away from the prostate I have read it could be linked to prostitas but I’m probably being paranoid and just a muscle strain.the diagnosis was a shock hoping everything would be benign, but it’s very load grade which just crept into Gleason 3+4 with a psa 3.85, the consultant said this is the best bad news I’ve given all day, so I know other people are in a worse situation they me. 

User
Posted 15 Aug 2026 at 12:57

Hi, Tony.

Yes, a biopsy can cause a temporary PSA rise. Good luck, with your next check. πŸ‘

User
Posted 16 Aug 2026 at 19:57
Thanks again Adrian your advice is very welcome, I’ve had a bit of a wobble with my last psa result, but I will continue with AS for now as my diagnosis is favourable.

And if I do look to have treatment in the future I would want to see if focal therapy is available to me as believe it would be and also if I can stay on AS for two years like yourself maybe treatments by then would improve πŸ™πŸ»

Thanks again πŸ‘πŸ»

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User
Posted 15 Jun 2026 at 07:30

Hi, Tony.

Welcome to the forum.

I'm not medically trained but your PSA levels are only very slightly above the normal range. Your prostate size is normal. The MRI pi-rads 3 and your PSA density are  indeterminate as to the likelihood of significantly prostate cancer.

It is possible that your slightly raised PSA level and the MRI result are due to to other non cancerous conditions such as prostatitis.

Your biopsy will show IF there are any cancerous cells and indicate how aggressive they are.

Most of us have been in your position and understand the anxiety diagnosis procedures and waiting for results cause. 

I hope the biopsy results are good, please keep us updated and good luck, mate.πŸ‘ 

Edited by member 15 Jun 2026 at 07:31  | Reason: Typo

User
Posted 15 Jun 2026 at 09:50

Thanks for the reply πŸ™πŸ» just now waiting for the biopsy which I’m not looking forward to, on paper my results don’t look so bad but the pessimist in me is thinking the worst, also getting pain around the groin area which worries me a bit even though the mri reports no spread outside the prostate, have read though groin pain can be associated with prostitas not if this is the though.

User
Posted 15 Jun 2026 at 13:54

Hi.

The biopsy is had was not bad at all. It was transrectal rather than transperineal. 

Obviously that means the ultrasound probe and biopsy tool go up the rectum.

But transperineal still requires the ultrasound probe to go in via the rectum even though the biopsy needles go in from outside the body.

The man who went in before me was absolutely terrified, completely and utterly mortified about something going up his bottom. 

When he came out he was "What is all the fuss about, easy easy, didn't feel a thing" 

I was OK with the idea of the biopsy and it went really easily.  There is some discomfort sure, but id rather do that than have a tooth out.

Just relax and wait for each test and result to come along. 

Your results are way less than mine and I came back all clear. 

Best regards Mick 

User
Posted 15 Jun 2026 at 15:01

Thanks Mick for the reply, I’m having the transpienal biopsy it doesn’t sound the most comfortable thing to have done and having it under local anesthetic as well 😬 also thanks for the encouraging thoughts regarding my test results, just the waiting now all the best πŸ‘πŸ» Tony

User
Posted 17 Jun 2026 at 21:26

Hi Tony

I had the TP biopsy but had done some reading up on it beforehand - the hospital actually sent out some very good information.

My surgeon said at the outset that I would have no pain and he was in the main correct.  My process started off with a freezing spray being applied to the perineum (the doc said it was like the spray they use on footballers). I did wince a bit!!  Then he put in the local anaesthetic - into the frozen area.  Afterwards he used a needle to test if the anaesthetic had taken affect - and it had in most places...  The sample needles went in OK and the samples (21 in my case) taken with the odd bit of discomfort.  The U/S probe also went in relatively easily, plenty of lube!!

The process did end up virtually painless just as promised.  The thing I wasn't expecting was to have to deal with the outflow of the copious quantity of lube!! I was given a pad and some very snazzy tightey whitey pants to wear home!!   It is an invasive procedure and not the most dignified process but it is soon over - and then onward to the results and a treatment pathway.

Hope it all goes well for you.

Best wishes - stay positive

CeePee

User
Posted 18 Jun 2026 at 12:54
I also had the TP biopsy 6 weeks ago. My hospital didn't get the memo about any spray, so first two jabs went in, not bad. The two jabs into the prostrate was a little uncomfortable, but that was all the discomfort I felt. Then straight onto the sampling bit.

Personally I found the probe up the bum the worst, they told me that it was the size of a mans thumb - Hmmm.

The lube coming out afterwards was interesting :)

The worst part was waiting for the results, that took 6 weeks, outsourced path testing.

Had a PSA of 5.3 then 5.4, no symptoms, just decided to get tested as I knew a few mates who had had prostrate cancer.

Results - out of 22 samples, 14 had traces of cancer. Gleason 3+4 = 7, TC2 NO MO, so all contained in the prostrate. Next step meetings with Oncology and the Surgeon to decide on treatment options.

User
Posted 16 Jul 2026 at 11:49

Hi, just been diagnosed with Gleason 3+4 low grade contained in prostate, out of 16 cores 3 contains cancer size 3m, so they recommend active surveillance for a year psa test every 3 months, one question has anyone experienced groin or pelvic discomfort since being diagnosed I’m experiencing some could be just a coincidence and I do have a quite physical job , would appreciate any feedback.

User
Posted 16 Jul 2026 at 12:44

Hi, Tony.

It's very unlikely that your groin and pelvis pains are Pca linked.

It's been commented on here many times that especially after a recent diagnosis, we  blame every ache, pain and other problem on cancer. 

I have arthritis and often get bone pains, it's taken me ages to reassure myself, that they are not connected to my PCa.

Good luck, with your active surveillance, mate, and please keep us informed how it goes.πŸ‘

Edited by member 17 Jul 2026 at 09:13  | Reason: Typo

User
Posted 16 Jul 2026 at 17:16

Hi Adrian, thanks for the reply, I think hopefully you’re right it’s just in the area which is not to far away from the prostate I have read it could be linked to prostitas but I’m probably being paranoid and just a muscle strain.the diagnosis was a shock hoping everything would be benign, but it’s very load grade which just crept into Gleason 3+4 with a psa 3.85, the consultant said this is the best bad news I’ve given all day, so I know other people are in a worse situation they me. 

User
Posted 17 Jul 2026 at 08:32

Hi

Your PSA is low so the likelihood that any aches and pains are related to prostate cancer is extremely low coupled with the fact your MPMRI and biopsy only evidenced low burden prostate cancer. 

What  I do think is important is to ensure your surveillance is active and action is taken if PSA starts to creep. My husband’s PSA was much higher than yours and he had a large prostate approx 80cc. He was diagnosed with Gleason 3-4 following private MPMRI and private biopsy etc. He had his surgery done privately at Royal Marsden hospital and following prostactomy a further three tumours were identified. Yes they were small .22cc, .14 cc , and .09cc. but the .14cc was 4-3. This did not change the overall grading but does evidence that MPMRI and biopsy do not always identify all tumours hence the need for you to watch that PSA carefully.

I do not say this to concern you but sometimes active surveillance is not as active as it could be. You are in an excellent position with low PSA and very little evidence of disease so as long as you can avoid radical treatment the better but just advocate for yourself if you have any concerns moving forward.

User
Posted 15 Aug 2026 at 11:12
Hi, I had my biopsy 7 weeks ago I’ve recently had my psa blood test and there was jump form 3.85-4.63 which was a surprise. Could the poking and prodding from the biopsy cause an artificial rise! My nurse didn’t seem to concerned about it and ask me to book another in six weeks.

Thanks Tony

User
Posted 15 Aug 2026 at 12:57

Hi, Tony.

Yes, a biopsy can cause a temporary PSA rise. Good luck, with your next check. πŸ‘

User
Posted 15 Aug 2026 at 20:28

Thanks Adrian for your reply, I’m just thinking that 7 weeks is past the time that it could affect it, but I’m hoping it has a bearing on it

User
Posted 16 Aug 2026 at 04:50

Hi, Tony.

The affect prostate biopies may have on PSA levels is usually deemed up to  6 weeks.  However, it is still possible that your small rise could be connected to your recent one.

A single  PSA rise can also be caused by many other non cancerous factors. An upward trend of results is more significant and a possible reason for concern.

Hopefully, your next PSA test might show that this small rise was a 'blip' rather than a trend.

I had my PSA regularly checked for several years, and every 3 months during my two years of active surveillance. It used to fluctuate a bit. Then results started to show an upward trend, which lead to a further MRI scan, another biopsy and RARP.

Good luck, mate. πŸ‘

Edited by member 16 Aug 2026 at 09:15  | Reason: Additional text

User
Posted 16 Aug 2026 at 11:36

Thanks Adrian again for the reply, before I was diagnosed my psa in May was 3.59 then in June 3.85, 

was then diagnosed 3+4 Gleason , 95% 3 5 % - 4 , active surveillance was recommended my next psa was 4.63 so there is a upward trend , it’s only been just over a month since I’ve been on active surveillance but already finding difficult with the scan anxiety.

Hope don’t mind me asking but how you doing now after surgery with the all the side effects.

Tony

Edited by member 16 Aug 2026 at 11:37  | Reason: Misprint

User
Posted 16 Aug 2026 at 12:50

Hi again, Tony.

Despite my active surveillance failing, I'm still a great fan of the treatment. It does require a particular mindset though. Some lads find it hard to live with knowing they have a cancer that may progress. There are lot of PSA checks as well, that can add to the anxiety.

You may not be psychologically suited to monitoring and find the process too worrying.

If you think you'd be better off going for radical treatment. Here's a useful video that gives various treatment options and their possible side effects. 

https://youtu.be/zYTU94-8pTc?si=xW83bOb0AVFQFD2l

My robotic surgery has been pretty successful so far. My bio contains full details. My advice would be carefully consider ALL options open to you. Look at possible side effects and pick which treatment suits your individual needs best.

Unfortunately there are no guaranteed outcomes with any treatment. You get good and bad stories about them all. Personal experiences do serve a purpose, but I'd be more inclined to look at the overall outcomes of thousands of men having certain treatments, rather than relying on the success or failure of a certain individual. If you see what I mean. πŸ‘

Edited by member 16 Aug 2026 at 19:39  | Reason: Add link

User
Posted 16 Aug 2026 at 19:57
Thanks again Adrian your advice is very welcome, I’ve had a bit of a wobble with my last psa result, but I will continue with AS for now as my diagnosis is favourable.

And if I do look to have treatment in the future I would want to see if focal therapy is available to me as believe it would be and also if I can stay on AS for two years like yourself maybe treatments by then would improve πŸ™πŸ»

Thanks again πŸ‘πŸ»

 
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