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Mets

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User
Posted 04 Jan 2019 at 18:01

Hi, 

Might be a silly question but can skull mets spread to the brain? 

Miffy
User
Posted 04 Jan 2019 at 18:42
Don't know is this is helpful but is conclusion from a US 11 year study.

"Conclusions

Brain metastasis from prostate cancer remains a rare phenomenon that most frequently occurs in the setting of widely disseminated bone and soft tissue disease. Patients with nonadenocarcinoma pathology are more likely to develop brain metastases. The MRI appearance is highly variable and prognosis is poor."

Barry
User
Posted 04 Jan 2019 at 19:06

Thanks Barry, don't suppose you could translate into layman's terms? embarassed

Miffy
User
Posted 04 Jan 2019 at 19:10
Brain mets are more likely from extensive lymph involvement than from skull mets but skull mets can produce similar symptoms to brain tumours. We have had a couple of members with mets to the jaw who have gone on to have brain mets as well, I think. Look up Andy Ripley for brain involvement.
"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 04 Jan 2019 at 19:13
Basically the quote says that brain mets are extremely rare, will usually present in a patient that has lots of spread to bones and soft organs and are usually from a prostate cancer that isn't your average adenocarcinoma.
"Life can only be understood backwards; but it must be lived forwards." Soren Kierkegaard

User
Posted 05 Jan 2019 at 10:30
As has been said, brain mets are unusual; but untreated skull mets will - eventually - grow into the brain. Even before that, if they grow on the inside of the skull, they are a 'space occupying lesion' - they are taking space reserved for the brain, and therefore apply pressure on the brain. Just like many brain tumours, which don't actually infiltrate the brain, but cause symptoms just by 'being there'.
 
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